Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50048561
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222105BDBM50222105(CHEMBL92814)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222094BDBM50222094(CHEMBL96305)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222105BDBM50222105(CHEMBL92814)
Affinity DataIC50: 0.700nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222098BDBM50222098(CHEMBL93161)
Affinity DataIC50: 1.10nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222096BDBM50222096(CHEMBL92648)
Affinity DataIC50: 1.20nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222108BDBM50222108(CHEMBL93028)
Affinity DataIC50: 1.30nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222094BDBM50222094(CHEMBL96305)
Affinity DataIC50: 1.5nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222107BDBM50222107(CHEMBL93650)
Affinity DataIC50: 1.60nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222109BDBM50222109(CHEMBL93059)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222107BDBM50222107(CHEMBL93650)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222098BDBM50222098(CHEMBL93161)
Affinity DataIC50: 2nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222101BDBM50222101(CHEMBL329635)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222097BDBM50222097(CHEMBL92851)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222096BDBM50222096(CHEMBL92648)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222084BDBM50222084(CHEMBL327632)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222110BDBM50222110(CHEMBL96629)
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222100BDBM50222100(CHEMBL329005)
Affinity DataIC50: 4.20nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222109BDBM50222109(CHEMBL93059)
Affinity DataIC50: 5nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222093BDBM50222093(CHEMBL178031)
Affinity DataIC50: 5.30nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222095BDBM50222095(CHEMBL91864)
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222099BDBM50222099(CHEMBL93140)
Affinity DataIC50: 7nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222099BDBM50222099(CHEMBL93140)
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222095BDBM50222095(CHEMBL91864)
Affinity DataIC50: 7.30nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222084BDBM50222084(CHEMBL327632)
Affinity DataIC50: 8.20nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222110BDBM50222110(CHEMBL96629)
Affinity DataIC50: 9nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222108BDBM50222108(CHEMBL93028)
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222098BDBM50222098(CHEMBL93161)
Affinity DataIC50: 9nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222103BDBM50222103(CHEMBL329792)
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222103BDBM50222103(CHEMBL329792)
Affinity DataIC50: 11nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222094BDBM50222094(CHEMBL96305)
Affinity DataIC50: 11nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222105BDBM50222105(CHEMBL92814)
Affinity DataIC50: 14nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222104BDBM50222104(CHEMBL93462)
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222110BDBM50222110(CHEMBL96629)
Affinity DataIC50: 17nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222109BDBM50222109(CHEMBL93059)
Affinity DataIC50: 20nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222101BDBM50222101(CHEMBL329635)
Affinity DataIC50: 22nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222097BDBM50222097(CHEMBL92851)
Affinity DataIC50: 25nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222102BDBM50222102(CHEMBL93910)
Affinity DataIC50: 25nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222108BDBM50222108(CHEMBL93028)
Affinity DataIC50: 42nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222106BDBM50222106(CHEMBL93639)
Affinity DataIC50: 44nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222096BDBM50222096(CHEMBL92648)
Affinity DataIC50: 51nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222103BDBM50222103(CHEMBL329792)
Affinity DataIC50: 63nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222107BDBM50222107(CHEMBL93650)
Affinity DataIC50: 65nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222097BDBM50222097(CHEMBL92851)
Affinity DataIC50: 72nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222099BDBM50222099(CHEMBL93140)
Affinity DataIC50: 170nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222084BDBM50222084(CHEMBL327632)
Affinity DataIC50: 220nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222101BDBM50222101(CHEMBL329635)
Affinity DataIC50: 400nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222093BDBM50222093(CHEMBL178031)
Affinity DataIC50: 500nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222100BDBM50222100(CHEMBL329005)
Affinity DataIC50: 500nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122372BDBM50122372(1-(2,6-dichlorophenyl)-6-(2,4-difluorophenylthio)-...)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222095BDBM50222095(CHEMBL91864)
Affinity DataIC50: 940nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed