Compile Data Set for Download or QSAR
maximum 50k data
Found 37 Enz. Inhib. hit(s) with all data for entry = 50012991
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataKi:  1.90nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125136(2-[2,3']Bipyridinyl-6'-yl-1-(2,3-dihydro-benzofura...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125124(CHEMBL433708 | [1-(2,3-Dihydro-benzofuran-5-yl)-1,...)
Affinity DataKi:  8.10nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50118253(1-Benzo[1,3]dioxol-5-yl-2-[5-(3,4-dimethoxy-phenyl...)
Affinity DataKi:  8.90nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125116(1-Benzo[1,3]dioxol-5-yl-2-[5-(4-methoxy-phenyl)-py...)
Affinity DataKi:  18nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125139(1-(2,3-Dihydro-benzofuran-5-yl)-2-[5-(2,3-dimethyl...)
Affinity DataKi:  24nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125121(CHEMBL349359 | [1-(2,3-Dihydro-benzofuran-5-yl)-1,...)
Affinity DataKi:  32nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125143(CHEMBL166018 | N-{3-[5-(1-Benzo[1,3]dioxol-5-yl-1,...)
Affinity DataKi:  51nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125118(1-Benzo[1,3]dioxol-5-yl-2-[5-(3,4-dimethoxy-phenyl...)
Affinity DataKi:  63nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125118(1-Benzo[1,3]dioxol-5-yl-2-[5-(3,4-dimethoxy-phenyl...)
Affinity DataKi:  63nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125142(CHEMBL349204 | N-{4-[5-(1-Benzo[1,3]dioxol-5-yl-1,...)
Affinity DataKi:  64nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125141((1-Benzo[1,3]dioxol-5-yl-1,3,4,9-tetrahydro-beta-c...)
Affinity DataKi:  78nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125135(1-Benzo[1,3]dioxol-5-yl-2-[5-(3,4-dimethoxy-phenyl...)
Affinity DataKi: >100nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125128(CHEMBL165117 | [5-(4-Amino-phenyl)-furan-2-yl]-(1-...)
Affinity DataKi:  123nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125144((1-Benzo[1,3]dioxol-5-yl-1,3,4,9-tetrahydro-beta-c...)
Affinity DataKi:  126nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125140(1-Benzo[1,3]dioxol-5-yl-2-[5-(4-chloro-phenyl)-pyr...)
Affinity DataKi:  126nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125129((1-Benzo[1,3]dioxol-5-yl-1,3,4,9-tetrahydro-beta-c...)
Affinity DataKi:  130nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125122(1-Benzo[1,3]dioxol-5-yl-2-[5-(4-methanesulfonyl-2-...)
Affinity DataKi:  132nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125127((1-Benzo[1,3]dioxol-5-yl-1,3,4,9-tetrahydro-beta-c...)
Affinity DataKi:  145nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125123(4-{2-[1-(2,3-Dihydro-benzofuran-5-yl)-1,3,4,9-tetr...)
Affinity DataKi:  154nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125131(CHEMBL350962 | [5-(3-Amino-phenyl)-furan-2-yl]-(1-...)
Affinity DataKi:  179nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125134(1-(2,3-Dihydro-benzofuran-5-yl)-2-[5-(4-methoxy-ph...)
Affinity DataKi:  188nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125134(1-(2,3-Dihydro-benzofuran-5-yl)-2-[5-(4-methoxy-ph...)
Affinity DataKi:  189nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125137((1-Benzo[1,3]dioxol-5-yl-1,3,4,9-tetrahydro-beta-c...)
Affinity DataKi:  219nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125130(1-Benzo[1,3]dioxol-5-yl-2-[5-(4-methoxy-phenyl)-py...)
Affinity DataKi:  246nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125130(1-Benzo[1,3]dioxol-5-yl-2-[5-(4-methoxy-phenyl)-py...)
Affinity DataKi:  246nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125133(1-Benzo[1,3]dioxol-5-yl-2-(5-p-tolyl-pyrimidin-2-y...)
Affinity DataKi:  543nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125126(1-Benzo[1,3]dioxol-5-yl-2-[5-(3-trifluoromethyl-ph...)
Affinity DataKi:  850nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125120(1-(2,3-Dihydro-benzofuran-5-yl)-2-{5-[4-(2-pyrroli...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125117((1-Benzo[1,3]dioxol-5-yl-3,4-dihydro-1H-benzo[4,5]...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125119(1-(3,4-Dimethoxy-phenyl)-2-[5-(4-methoxy-phenyl)-p...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125132(((R)-1-Benzo[1,3]dioxol-5-yl-1,3,4,9-tetrahydro-be...)
Affinity DataIC50:  67nMAssay Description:Inhibition of PDE5 (Phosphodiesterase) from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125146(4-{3-[5-(1-Benzo[1,3]dioxol-5-yl-1,3,4,9-tetrahydr...)
Affinity DataIC50:  95nMAssay Description:Inhibition of PDE5 (Phosphodiesterase) from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125147(4-{4-[5-(1-Benzo[1,3]dioxol-5-yl-1,3,4,9-tetrahydr...)
Affinity DataIC50:  100nMAssay Description:Inhibition of PDE5 (Phosphodiesterase) from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125138((1-Benzo[1,3]dioxol-5-yl-1,3,4,9-tetrahydro-beta-c...)
Affinity DataIC50:  105nMAssay Description:Inhibition of PDE5 (Phosphodiesterase) from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125145((1-Benzo[1,3]dioxol-5-yl-1,3,4,9-tetrahydro-beta-c...)
Affinity DataIC50:  750nMAssay Description:Inhibition of PDE5 (Phosphodiesterase) from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125125(((S)-1-Benzo[1,3]dioxol-5-yl-1,3,4,9-tetrahydro-be...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE5 (Phosphodiesterase) from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed