Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50037144
TargetSigma non-opioid intracellular receptor 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128107(1-[2-(4-Chloro-phenoxy)-1-methyl-ethyl]-4-methyl-p...)
Affinity DataKi:  0.340nMAssay Description:Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128111(1-(5-Benzo[1,3]dioxol-5-yl-penta-2,4-dienyl)-piper...)
Affinity DataKi:  0.860nMAssay Description:Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128110(1-[2-(4-Chloro-phenoxy)-ethyl]-4-methyl-piperidine...)
Affinity DataKi:  0.860nMAssay Description:Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128104(1-[3-(4-Chloro-phenoxy)-2-methyl-propyl]-4-methyl-...)
Affinity DataKi:  1.09nMAssay Description:Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128108(1-[2-(4-Chloro-phenoxy)-1-methyl-ethyl]-4-methyl-p...)
Affinity DataKi:  1.18nMAssay Description:Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128113(1-[3-(4-Chloro-phenoxy)-butyl]-4-methyl-piperidine...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128101(1-[3-(4-Chloro-phenoxy)-2-methyl-propyl]-4-methyl-...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128112(1-[3-(4-Chloro-phenoxy)-propyl]-4-methyl-piperidin...)
Affinity DataKi:  1.78nMAssay Description:Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128105(1-[2-(4-Chloro-phenoxy)-propyl]-4-methyl-piperidin...)
Affinity DataKi:  1.81nMAssay Description:Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128109(1-[3-(4-Chloro-phenoxy)-butyl]-4-methyl-piperidine...)
Affinity DataKi:  1.83nMAssay Description:Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128103(1-[3-(4-Chloro-phenoxy)-1-methyl-propyl]-4-methyl-...)
Affinity DataKi:  2.21nMAssay Description:Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50084012(CHEMBL53649 | CHEMBL544992 | (3,4-Dichloro-phenyl)...)
Affinity DataKi:  2.51nMAssay Description:Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128106(1-[3-(4-Chloro-phenoxy)-1-methyl-propyl]-4-methyl-...)
Affinity DataKi:  2.69nMAssay Description:Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50035131((1S,9S,13S)-1,13-dimethyl-10-(3-methylbut-2-enyl)-...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128105(1-[2-(4-Chloro-phenoxy)-propyl]-4-methyl-piperidin...)
Affinity DataKi:  3.38nMAssay Description:Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128110(1-[2-(4-Chloro-phenoxy)-ethyl]-4-methyl-piperidine...)
Affinity DataKi:  3.70nMAssay Description:Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128107(1-[2-(4-Chloro-phenoxy)-1-methyl-ethyl]-4-methyl-p...)
Affinity DataKi:  3.73nMAssay Description:Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128103(1-[3-(4-Chloro-phenoxy)-1-methyl-propyl]-4-methyl-...)
Affinity DataKi:  7.79nMAssay Description:Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128112(1-[3-(4-Chloro-phenoxy)-propyl]-4-methyl-piperidin...)
Affinity DataKi:  9.65nMAssay Description:Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128109(1-[3-(4-Chloro-phenoxy)-butyl]-4-methyl-piperidine...)
Affinity DataKi:  12nMAssay Description:Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128102(1-[2-(4-Chloro-phenoxy)-propyl]-4-methyl-piperidin...)
Affinity DataKi:  12.6nMAssay Description:Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128104(1-[3-(4-Chloro-phenoxy)-2-methyl-propyl]-4-methyl-...)
Affinity DataKi:  14.5nMAssay Description:Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128101(1-[3-(4-Chloro-phenoxy)-2-methyl-propyl]-4-methyl-...)
Affinity DataKi:  18.7nMAssay Description:Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128108(1-[2-(4-Chloro-phenoxy)-1-methyl-ethyl]-4-methyl-p...)
Affinity DataKi:  27.5nMAssay Description:Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128113(1-[3-(4-Chloro-phenoxy)-butyl]-4-methyl-piperidine...)
Affinity DataKi:  30.1nMAssay Description:Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128102(1-[2-(4-Chloro-phenoxy)-propyl]-4-methyl-piperidin...)
Affinity DataKi:  35.1nMAssay Description:Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128106(1-[3-(4-Chloro-phenoxy)-1-methyl-propyl]-4-methyl-...)
Affinity DataKi:  37nMAssay Description:Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed