Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 1340 Sort by
TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 7.42E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM10949(CHEMBL75121 | 3-(4-{[benzyl(methyl)amino]methyl}ph...)
Affinity DataIC50: 4.89E+4nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataKi:  20.5nM ΔG°:  -45.6kJ/mole IC50: 23.1nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10949(CHEMBL75121 | 3-(4-{[benzyl(methyl)amino]methyl}ph...)
Affinity DataKi:  21.7nM ΔG°:  -45.5kJ/mole IC50: 44.5nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed