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Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 1340
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataKi:  20.5nM ΔG°:  -45.6kJ/mole IC50:  23.1nMpH: 8.0 T: 37°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
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PDB3D3D Structure (crystal)

TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10949(3-(4-{[Benzyl(methyl)amino]methyl}-phenyl)-6,7-dim...)
Affinity DataKi:  21.7nM ΔG°:  -45.5kJ/mole IC50:  44.5nMpH: 8.0 T: 37°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  7.42E+3nMpH: 8.0 T: 37°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM10949(3-(4-{[Benzyl(methyl)amino]methyl}-phenyl)-6,7-dim...)
Affinity DataIC50:  4.89E+4nMpH: 8.0 T: 37°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed