Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 361
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1057BDBM1057(3-[N-(Phthalimidomethyl)amino]-5-ethyl-6-methylpyr...)
Affinity DataIC50: 30nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1058BDBM1058(2-{[(6-methyl-2-oxo-5-propyl-1,2-dihydropyridin-3-...)
Affinity DataIC50: 58nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1059BDBM1059(2-{[(5-butyl-6-methyl-2-oxo-1,2-dihydropyridin-3-y...)
Affinity DataIC50: 128nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1056BDBM1056(2-{[(5,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)am...)
Affinity DataIC50: 218nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1060BDBM1060(2-{[(6-ethyl-5-methyl-2-oxo-1,2-dihydropyridin-3-y...)
Affinity DataIC50: 887nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1054BDBM1054(2-{[(2-oxo-1,2-dihydropyridin-3-yl)amino]methyl}-2...)
Affinity DataIC50: 1.66E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1066BDBM1066(2-[2-(5-ethyl-6-methyl-2-oxo-1,2-dihydropyridin-3-...)
Affinity DataIC50: 3.70E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1061BDBM1061(3-[N-(Phthalimidomethyl)amino]-5,6,7,8-tetrahydroq...)
Affinity DataIC50: 3.70E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1072BDBM1072(2-[2-(5-ethyl-2-methoxy-6-methylpyridin-3-yl)ethyl...)
Affinity DataIC50: 6.20E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1055BDBM1055(2-{[(6-methyl-2-oxo-1,2-dihydropyridin-3-yl)amino]...)
Affinity DataIC50: 8.10E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1071BDBM1071(2-[(5-ethyl-2-methoxy-6-methylpyridin-3-yl)methyl]...)
Affinity DataIC50: 1.60E+4nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1065BDBM1065(2-[(5-ethyl-6-methyl-2-oxo-1,2-dihydropyridin-3-yl...)
Affinity DataIC50: 2.65E+4nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1062BDBM1062(2-{2-[(5-ethyl-6-methyl-2-oxo-1,2-dihydropyridin-3...)
Affinity DataIC50: 4.50E+4nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1070BDBM1070(2-[(E)-2-(5-ethyl-6-methyl-2-oxo-1,2-dihydropyridi...)
Affinity DataIC50: 5.40E+4nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1063BDBM1063(2-{3-[(5-ethyl-6-methyl-2-oxo-1,2-dihydropyridin-3...)
Affinity DataIC50: 1.90E+5nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1067BDBM1067(2-[3-(5-ethyl-6-methyl-2-oxo-1,2-dihydropyridin-3-...)
Affinity DataIC50: 2.10E+5nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1068BDBM1068(2-[2-(5-ethyl-6-methyl-2-oxo-1,2-dihydropyridin-3-...)
Affinity DataIC50: 3.00E+5nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1069BDBM1069(2-[2-(5-ethyl-6-methyl-2-oxo-1,2-dihydropyridin-3-...)
Affinity DataIC50: 3.00E+5nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1073BDBM1073(2-[3-(5-ethyl-2-methoxy-6-methylpyridin-3-yl)propy...)
Affinity DataIC50: 3.00E+5nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1074BDBM1074(2-[2-(5-ethyl-2-methoxy-6-methylpyridin-3-yl)-2-ox...)
Affinity DataIC50: 3.00E+5nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1075BDBM1075(2-[2-(5-ethyl-2-methoxy-6-methylpyridin-3-yl)-2-hy...)
Affinity DataIC50: 3.00E+5nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1064BDBM1064(2-[2-(2-oxo-1,2-dihydropyridin-3-yl)ethyl]-2,3-dih...)
Affinity DataIC50: 3.00E+5nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed