Compile Data Set for Download or QSAR
maximum 50k data
Found 21 Enz. Inhib. hit(s) with all data for entry = 50035308
TargetMelanocortin receptor 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130009((4S,15R,18S,21S,24S)-5-((S)-2-Acetylamino-hexanoyl...)
Affinity DataIC50:  3nMAssay Description:Binding affinity towards human melanocortin 4 receptor (hMC4R) using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130014((R)-2-Acetylamino-N-(4-{acetyl-[2-(1H-indol-3-yl)-...)
Affinity DataIC50:  7.70nMAssay Description:Binding affinity towards human melanocortin 4 receptor (hMC4R) using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130009((4S,15R,18S,21S,24S)-5-((S)-2-Acetylamino-hexanoyl...)
Affinity DataIC50:  23nMAssay Description:Binding affinity towards human melanocortin 3 receptor (hMC3R) using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50130014((R)-2-Acetylamino-N-(4-{acetyl-[2-(1H-indol-3-yl)-...)
Affinity DataIC50:  51nMAssay Description:Binding affinity towards mouse Melanocortin 1 receptor (mMC1R) using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130014((R)-2-Acetylamino-N-(4-{acetyl-[2-(1H-indol-3-yl)-...)
Affinity DataIC50:  280nMAssay Description:Binding affinity towards human melanocortin 3 receptor (hMC3R) using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130014((R)-2-Acetylamino-N-(4-{acetyl-[2-(1H-indol-3-yl)-...)
Affinity DataIC50:  3.50E+3nMAssay Description:Intracellular levels of cAMP in HEK 293 cells expressing human melanocortin 4 receptor (hMC4R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130014((R)-2-Acetylamino-N-(4-{acetyl-[2-(1H-indol-3-yl)-...)
Affinity DataIC50:  3.50E+3nMAssay Description:Intracellular levels of cAMP in HEK 293 cells expressing human melanocortin 4 receptor (hMC4R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50130013((S)-2-Acetylamino-N-[4-(acetyl-methyl-amino)-cyclo...)
Affinity DataIC50:  9.00E+3nMAssay Description:Binding affinity towards mouse Melanocortin 1 receptor (mMC1R) using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130011((S)-2-Acetylamino-N-(4-{acetyl-[2-(1H-indol-3-yl)-...)
Affinity DataIC50:  9.25E+3nMAssay Description:Binding affinity towards human melanocortin 4 receptor (hMC4R) using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50130012(CHEMBL75185 | N-{4-[Acetyl-(4-guanidino-butyl)-ami...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity towards mouse Melanocortin 1 receptor (mMC1R) using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50130011((S)-2-Acetylamino-N-(4-{acetyl-[2-(1H-indol-3-yl)-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Binding affinity towards mouse Melanocortin 1 receptor (mMC1R) using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130013((S)-2-Acetylamino-N-[4-(acetyl-methyl-amino)-cyclo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity towards human melanocortin 4 receptor (hMC4R) using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130012(CHEMBL75185 | N-{4-[Acetyl-(4-guanidino-butyl)-ami...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity towards human melanocortin 4 receptor (hMC4R) using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130011((S)-2-Acetylamino-N-(4-{acetyl-[2-(1H-indol-3-yl)-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Binding affinity towards human melanocortin 3 receptor (hMC3R) using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130014((R)-2-Acetylamino-N-(4-{acetyl-[2-(1H-indol-3-yl)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity towards human melanocortin 3 receptor (hMC3R) using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130012(CHEMBL75185 | N-{4-[Acetyl-(4-guanidino-butyl)-ami...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity towards human melanocortin 3 receptor (hMC3R) using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130013((S)-2-Acetylamino-N-[4-(acetyl-methyl-amino)-cyclo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity towards human melanocortin 3 receptor (hMC3R) using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50130014((R)-2-Acetylamino-N-(4-{acetyl-[2-(1H-indol-3-yl)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity towards mouse Melanocortin 1 receptor (mMC1R) using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130014((R)-2-Acetylamino-N-(4-{acetyl-[2-(1H-indol-3-yl)-...)
Affinity DataEC50:  680nMAssay Description:Intracellular levels of cAMP in HEK 293 cells expressing human melanocortin 4 receptor (hMC4R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130009((4S,15R,18S,21S,24S)-5-((S)-2-Acetylamino-hexanoyl...)
Affinity DataEC50:  0.170nMAssay Description:Intracellular levels of cAMP in HEK 293 cells expressing human melanocortin 4 receptor (hMC4R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130014((R)-2-Acetylamino-N-(4-{acetyl-[2-(1H-indol-3-yl)-...)
Affinity DataEC50:  680nMAssay Description:Intracellular levels of cAMP in HEK 293 cells expressing human melanocortin 4 receptor (hMC4R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed