Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50013638
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132732BDBM50132732((S)-1-(2,6-difluorobenzyl)-5-(3-methoxyphenyl)-6-m...)
Affinity DataKi:  5nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132755BDBM50132755(1-(2,6-Difluoro-benzyl)-3-[(R)-2-(2-methoxy-benzyl...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132771BDBM50132771(1-(2,6-Difluoro-benzyl)-3-[(R)-2-(3-methoxy-benzyl...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132768BDBM50132768(1-(2,6-Difluoro-benzyl)-5-(3-methoxy-phenyl)-6-met...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132728BDBM50132728(1-(2,6-Difluoro-benzyl)-5-(3-methoxy-phenyl)-6-met...)
Affinity DataKi:  34nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132746BDBM50132746(1-(2,6-Difluoro-benzyl)-5-(3-methoxy-phenyl)-6-met...)
Affinity DataKi:  70nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132761BDBM50132761(3-((R)-2-Benzylamino-1-methyl-ethyl)-1-(2,6-difluo...)
Affinity DataKi:  75nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132749BDBM50132749(1-(2,6-Difluoro-benzyl)-3-[(R)-2-(3-fluoro-benzyla...)
Affinity DataKi:  85nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132764BDBM50132764(1-(2,6-Difluoro-benzyl)-3-[(R)-2-(2-fluoro-benzyla...)
Affinity DataKi:  90nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132752BDBM50132752(3-[(R)-2-(Benzyl-methyl-amino)-1-methyl-ethyl]-1-(...)
Affinity DataKi:  150nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132755BDBM50132755(1-(2,6-Difluoro-benzyl)-3-[(R)-2-(2-methoxy-benzyl...)
Affinity DataKi:  160nMAssay Description:Binding affinity towards monkey gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132759BDBM50132759(1-(2,6-Difluoro-benzyl)-3-((R)-2-isobutylamino-1-m...)
Affinity DataKi:  190nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132751BDBM50132751(1-(2,6-Difluoro-benzyl)-3-[(R)-2-(4-fluoro-benzyla...)
Affinity DataKi:  250nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132760BDBM50132760(3-(1-Benzyl-pyrrolidin-3-yl)-1-(2,6-difluoro-benzy...)
Affinity DataKi:  280nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132747BDBM50132747(1-(2,6-Difluoro-benzyl)-3-[(S)-2-(2-methoxy-benzyl...)
Affinity DataKi:  320nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132763BDBM50132763(3-((S)-2-Benzylamino-1-methyl-ethyl)-1-(2,6-difluo...)
Affinity DataKi:  370nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132767BDBM50132767(1-(2,6-Difluoro-benzyl)-5-(3-methoxy-phenyl)-6-met...)
Affinity DataKi:  400nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132762BDBM50132762(3-((R)-2-Cyclopentylamino-1-methyl-ethyl)-1-(2,6-d...)
Affinity DataKi:  430nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132765BDBM50132765(1-(2,6-Difluoro-benzyl)-3-[(S)-2-(2-fluoro-benzyla...)
Affinity DataKi:  550nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132754BDBM50132754(3-[(R)-2-(Cyclopropylmethyl-methyl-amino)-1-methyl...)
Affinity DataKi:  590nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132756BDBM50132756(1-(2,6-Difluoro-benzyl)-3-[(R)-2-(4-methoxy-benzyl...)
Affinity DataKi:  720nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132753BDBM50132753(3-[(R)-2-(Cyclopropylmethyl-amino)-1-methyl-ethyl]...)
Affinity DataKi:  780nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132750BDBM50132750(3-((S)-2-Cyclopentylamino-1-methyl-ethyl)-1-(2,6-d...)
Affinity DataKi:  950nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132748BDBM50132748(1-(2,6-Difluoro-benzyl)-3-((S)-2-isobutylamino-1-m...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132758BDBM50132758(3-[(S)-2-(Cyclopropylmethyl-amino)-1-methyl-ethyl]...)
Affinity DataKi:  1.60E+3nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132772BDBM50132772(1-(2,6-Difluoro-benzyl)-5-(3-methoxy-phenyl)-6-met...)
Affinity DataKi:  1.80E+3nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132766BDBM50132766(3-[(S)-2-(Benzyl-methyl-amino)-1-methyl-ethyl]-1-(...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132757BDBM50132757(3-[(S)-2-(Cyclopropylmethyl-methyl-amino)-1-methyl...)
Affinity DataKi:  7.00E+3nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132769BDBM50132769(1-(2,6-Difluoro-benzyl)-5-(3-methoxy-phenyl)-6-met...)
Affinity DataKi:  8.30E+3nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132755BDBM50132755(1-(2,6-Difluoro-benzyl)-3-[(R)-2-(2-methoxy-benzyl...)
Affinity DataKi:  1.27E+4nMAssay Description:Binding affinity towards rat gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132770BDBM50132770(1-(2,6-Difluoro-benzyl)-5-(3-methoxy-phenyl)-6-met...)
Affinity DataKi:  1.50E+4nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed