Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50000012
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18133BDBM18133(2-aminoacetic acid | [14C]Glycine | CHEMBL773 | Gl...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibitory concentration required to inhibit [3H]strychnine binding to N-methyl-D-aspartate glutamate receptor 1 of rat spinal cord membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000101BDBM50000101(CHEMBL311110 | 2,5-Dihydro-1H-pyrrole-3-carboxylic...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibitory concentration required to inhibit [3H]strychnine binding to N-methyl-D-aspartate glutamate receptor 1 of rat spinal cord membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000102BDBM50000102(omega-aminopropionic acid | Alanine-beta | beta-am...)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibitory concentration of the compound required to inhibit [3H]-strychnine binding to N-methyl-D-aspartate glutamate receptor 1 of rat spinal cord ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000105BDBM50000105(pyrrolidine-2-carboxylic acid | CHEMBL72275 | prol...)
Affinity DataIC50: 1.72E+4nMAssay Description:Inhibitory concentration required to inhibit [3H]strychnine binding to N-methyl-D-aspartate glutamate receptor 1 of rat spinal cord membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000104BDBM50000104(CHEMBL310435 | Azetidine-3-carboxylic acid)
Affinity DataIC50: 2.37E+4nMAssay Description:Inhibitory concentration required to inhibit [3H]strychnine binding to N-methyl-D-aspartate glutamate receptor 1 of rat spinal cord membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000109BDBM50000109(D-alpha-aminopropionic acid | D-Alanin | CHEMBL666...)
Affinity DataIC50: 9.09E+4nMAssay Description:Inhibitory concentration of the compound required to inhibit [3H]-strychnine binding to N-methyl-D-aspartate glutamate receptor 1 of rat spinal cord ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000106BDBM50000106(Piperidine-4-carboxylic acid | Piperidine-4-carbox...)
Affinity DataIC50: 9.41E+4nMAssay Description:Inhibitory concentration required to inhibit [3H]strychnine binding to N-methyl-D-aspartate glutamate receptor 1 of rat spinal cord membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000099BDBM50000099((S)-alanine | CHEMBL279597 | Ala | (S)-2-aminoprop...)
Affinity DataIC50: 1.98E+5nMAssay Description:Inhibitory concentration required to inhibit [3H]strychnine binding to N-methyl-D-aspartate glutamate receptor 1 of rat spinal cord membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000103BDBM50000103(CHEMBL310623 | 2,5-Dihydro-1H-pyrrole-2-carboxylic...)
Affinity DataIC50: 2.42E+5nMAssay Description:Inhibitory concentration required to inhibit [3H]strychnine binding to N-methyl-D-aspartate glutamate receptor 1 of rat spinal cord membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000108BDBM50000108(CHEMBL33592 | azetidine-2-carboxylic acid)
Affinity DataIC50: 3.99E+5nMAssay Description:Inhibitory concentration required to inhibit [3H]strychnine binding to N-methyl-D-aspartate glutamate receptor 1 of rat spinal cord membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000100BDBM50000100((S)-2-pyrrolidinecarboxylic acid | CHEMBL54922 | L...)
Affinity DataIC50: 4.14E+5nMAssay Description:Inhibitory concentration required to inhibit [3H]strychnine binding to N-methyl-D-aspartate glutamate receptor 1 of rat spinal cord membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000107BDBM50000107(CHEMBL432561 | 1-Methyl-1,2,5,6-tetrahydro-pyridin...)
Affinity DataIC50: 6.94E+5nMAssay Description:Inhibitory concentration required to inhibit [3H]strychnine binding to N-methyl-D-aspartate glutamate receptor 1 of rat spinal cord membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed