Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 1859
TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14597(2-[3-Amino-3-fluoro-4-(isopropylamino)-1,1-bipheny...)
Affinity DataIC50:  340nMpH: 8.0 T: 2°CAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14596(2-[3-Amino-4-(benzylamino)-3-fluoro-1,1-biphenyl-2...)
Affinity DataIC50:  500nMpH: 8.0 T: 2°CAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14597(2-[3-Amino-3-fluoro-4-(isopropylamino)-1,1-bipheny...)
Affinity DataIC50:  950nMpH: 8.0 T: 2°CAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14594(N-[(4-carbamimidoylphenyl)methyl]-2-{2,6-difluoro-...)
Affinity DataIC50:  1.56E+3nMpH: 8.0 T: 2°CAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14601(CHEMBL125585 | N-[(4-carbamimidoylphenyl)methyl]-2...)
Affinity DataIC50:  2.50E+3nMpH: 8.0 T: 2°CAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14600(N-[(4-carbamimidoylphenyl)methyl]-2-{2-hydroxy-6-p...)
Affinity DataIC50:  2.70E+3nMpH: 8.0 T: 2°CAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14602(Benzoquinone Analog 54 | N-[(4-carbamimidoylphenyl...)
Affinity DataIC50:  2.80E+3nMpH: 8.0 T: 2°CAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14595(N-[(4-carbamimidoylphenyl)methyl]-2-{2-fluoro-6-ph...)
Affinity DataIC50:  3.98E+3nMpH: 8.0 T: 2°CAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14600(N-[(4-carbamimidoylphenyl)methyl]-2-{2-hydroxy-6-p...)
Affinity DataIC50:  6.80E+3nMpH: 8.0 T: 2°CAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14595(N-[(4-carbamimidoylphenyl)methyl]-2-{2-fluoro-6-ph...)
Affinity DataIC50:  7.00E+3nMpH: 8.0 T: 2°CAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14599(CHEMBL333980 | N-[(4-carbamimidoylphenyl)methyl]-2...)
Affinity DataIC50:  7.90E+3nMpH: 8.0 T: 2°CAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14598(N-[(4-carbamimidoylphenyl)methyl]-2-{2-methoxy-6-p...)
Affinity DataIC50:  9.50E+3nMpH: 8.0 T: 2°CAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14596(2-[3-Amino-4-(benzylamino)-3-fluoro-1,1-biphenyl-2...)
Affinity DataIC50:  1.00E+4nMpH: 8.0 T: 2°CAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14599(CHEMBL333980 | N-[(4-carbamimidoylphenyl)methyl]-2...)
Affinity DataIC50:  1.47E+4nMpH: 8.0 T: 2°CAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14594(N-[(4-carbamimidoylphenyl)methyl]-2-{2,6-difluoro-...)
Affinity DataIC50:  1.64E+4nMpH: 8.0 T: 2°CAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14598(N-[(4-carbamimidoylphenyl)methyl]-2-{2-methoxy-6-p...)
Affinity DataIC50:  2.50E+4nMpH: 8.0 T: 2°CAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14603(N-[(4-carbamimidoylphenyl)methyl]-2-[2,6-difluoro-...)
Affinity DataIC50:  2.69E+4nMpH: 8.0 T: 2°CAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14598(N-[(4-carbamimidoylphenyl)methyl]-2-{2-methoxy-6-p...)
Affinity DataIC50: >3.00E+4nMpH: 8.0 T: 2°CAssay Description:Human Factor Xa and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14599(CHEMBL333980 | N-[(4-carbamimidoylphenyl)methyl]-2...)
Affinity DataIC50: >3.00E+4nMpH: 8.0 T: 2°CAssay Description:Human Factor Xa and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14600(N-[(4-carbamimidoylphenyl)methyl]-2-{2-hydroxy-6-p...)
Affinity DataIC50: >3.00E+4nMpH: 8.0 T: 2°CAssay Description:Human Factor Xa and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14601(CHEMBL125585 | N-[(4-carbamimidoylphenyl)methyl]-2...)
Affinity DataIC50: >3.00E+4nMpH: 8.0 T: 2°CAssay Description:Human Factor Xa and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14602(Benzoquinone Analog 54 | N-[(4-carbamimidoylphenyl...)
Affinity DataIC50: >3.00E+4nMpH: 8.0 T: 2°CAssay Description:Human Factor Xa and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14603(N-[(4-carbamimidoylphenyl)methyl]-2-[2,6-difluoro-...)
Affinity DataIC50: >3.00E+4nMpH: 8.0 T: 2°CAssay Description:Human Factor Xa and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14597(2-[3-Amino-3-fluoro-4-(isopropylamino)-1,1-bipheny...)
Affinity DataIC50: >3.00E+4nMpH: 8.0 T: 2°CAssay Description:Human Factor Xa and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14595(N-[(4-carbamimidoylphenyl)methyl]-2-{2-fluoro-6-ph...)
Affinity DataIC50: >3.00E+4nMpH: 8.0 T: 2°CAssay Description:Human Factor Xa and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14594(N-[(4-carbamimidoylphenyl)methyl]-2-{2,6-difluoro-...)
Affinity DataIC50: >3.00E+4nMpH: 8.0 T: 2°CAssay Description:Human Factor Xa and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14602(Benzoquinone Analog 54 | N-[(4-carbamimidoylphenyl...)
Affinity DataIC50: >3.00E+4nMpH: 8.0 T: 2°CAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14601(CHEMBL125585 | N-[(4-carbamimidoylphenyl)methyl]-2...)
Affinity DataIC50: >3.00E+4nMpH: 8.0 T: 2°CAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14603(N-[(4-carbamimidoylphenyl)methyl]-2-[2,6-difluoro-...)
Affinity DataIC50: >3.00E+4nMpH: 8.0 T: 2°CAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14596(2-[3-Amino-4-(benzylamino)-3-fluoro-1,1-biphenyl-2...)
Affinity DataIC50: >3.00E+4nMpH: 8.0 T: 2°CAssay Description:Human Factor Xa and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed