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Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50000231
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003237(2,2-Dimethyl-butyric acid 2-(1-hydroxy-ethyl)-8-[2...)
Affinity DataIC50:  7.60nMAssay Description:The compound was tested in vitro for inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003236(2,2-Dimethyl-butyric acid 2-hydroxymethyl-8-[2-(4-...)
Affinity DataIC50:  11nMAssay Description:The compound was tested in vitro for inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003240(2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-te...)
Affinity DataIC50:  12nMAssay Description:The compound was tested in vitro for inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003239(2,2-Dimethyl-butyric acid 2-hydroxy-8-[2-(4-hydrox...)
Affinity DataIC50:  13nMAssay Description:The compound was tested in vitro for inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003235(2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrah...)
Affinity DataIC50:  18nMAssay Description:The compound was tested in vitro for inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003241(2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-te...)
Affinity DataIC50:  20nMAssay Description:The compound was tested in vitro for inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011036((S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-...)
Affinity DataIC50:  28nMAssay Description:The compound was tested in vitro for inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed