Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50000238
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003319(CHEMBL132216 | 3-(2-{5-Guanidino-2-[(2-mercapto-be...)
Affinity DataKi:  4nMAssay Description:Inhibition of [3H]Mba-(N-Me)Arg-Gly-Asp-Man binding to fibrinogen receptor of human platelets reconstituted in liposomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003319(CHEMBL132216 | 3-(2-{5-Guanidino-2-[(2-mercapto-be...)
Affinity DataIC50: 90nMAssay Description:Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003322(CHEMBL2370660 | 3-(2-{2-[(2-Acetylamino-3-mercapto...)
Affinity DataKi:  175nMAssay Description:Inhibition of [3H]Mba-(N-Me)Arg-Gly-Asp-Man binding to fibrinogen receptor of human platelets reconstituted in liposomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003316(CHEMBL340340 | 3-{2-[5-Guanidino-2-(2-mercapto-ben...)
Affinity DataIC50: 290nMAssay Description:Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003322(CHEMBL2370660 | 3-(2-{2-[(2-Acetylamino-3-mercapto...)
Affinity DataIC50: 355nMAssay Description:Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003318(CHEMBL2370663 | 3-(2-{2-[(2-Acetylamino-3-mercapto...)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003317(CHEMBL339832 | [18-(3-Guanidino-propyl)-2,8,11,14,...)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of [3H]Mba-(N-Me)Arg-Gly-Asp-Man binding to GPIIb/IIIa from human platelets reconstituted in liposomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003321(CHEMBL130189 | 3-{2-[2-(2-Acetylamino-3-mercapto-p...)
Affinity DataKi:  3.13E+3nMAssay Description:Inhibition of [3H]Mba-(N-Me)Arg-Gly-Asp-Man binding to Fibrinogen Receptor from human platelets reconstituted in liposomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003325(CHEMBL2370661 | 3-{2-[2-(2-Acetylamino-3-mercapto-...)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of [3H]Mba-(N-Me)Arg-Gly-Asp-Man binding to fibrinogen receptor of human platelets reconstituted in liposomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003325(CHEMBL2370661 | 3-{2-[2-(2-Acetylamino-3-mercapto-...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003313(CHEMBL2370659 | 3-{2-[2-(2-Acetylamino-3-mercapto-...)
Affinity DataIC50: 4.12E+3nMAssay Description:Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003317(CHEMBL339832 | [18-(3-Guanidino-propyl)-2,8,11,14,...)
Affinity DataIC50: 5.26E+3nMAssay Description:Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003323(3-[2-(2-{2-[2-(2-Amino-acetylamino)-3-mercapto-3-m...)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003315(CHEMBL421247 | [5-Benzyl-17-(3-guanidino-propyl)-4...)
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003315(CHEMBL421247 | [5-Benzyl-17-(3-guanidino-propyl)-4...)
Affinity DataKi:  1.85E+4nMAssay Description:Inhibition of [3H]Mba-(N-Me)Arg-Gly-Asp-Man binding to GPIIb/IIIa from human platelets reconstituted in liposomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003321(CHEMBL130189 | 3-{2-[2-(2-Acetylamino-3-mercapto-p...)
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003314(CHEMBL129782 | [18-(3-Guanidino-propyl)-2,5,11,14,...)
Affinity DataIC50: 7.66E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003314(CHEMBL129782 | [18-(3-Guanidino-propyl)-2,5,11,14,...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of [3H]Mba-(N-Me)Arg-Gly-Asp-Man binding to GPIIb/IIIa from human platelets reconstituted in liposomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003324([3,21-Dibenzyl-24-carboxymethyl-12,30-bis-(3-guani...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003320(CHEMBL450009 | [15-(3-Guanidino-propyl)-2,8,11,14,...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed