Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50000239
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230131BDBM50230131(SKF-107260)
Affinity DataKi:  4nMAssay Description:Inhibition of [3H]-107260 binding to purified GPIIb/IIIa of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230131BDBM50230131(SKF-107260)
Affinity DataIC50: 90nMAssay Description:Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003330BDBM50003330(CHEMBL423881 | (5-{[2-(Benzoyl-methyl-amino)-5-gua...)
Affinity DataKi:  106nMAssay Description:Inhibition of [3H]-107260 binding to purified GPIIb/IIIa of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230132BDBM50230132(SKF-106760 | CHEMBL324568)
Affinity DataKi:  175nMAssay Description:Inhibition of [3H]-107260 binding to purified GPIIb/IIIa of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003329BDBM50003329(CHEMBL130188 | (5-{[2-(Acetyl-methyl-amino)-5-guan...)
Affinity DataKi:  271nMAssay Description:Inhibition of [3H]-107260 binding to purified GPIIb/IIIa of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230132BDBM50230132(SKF-106760 | CHEMBL324568)
Affinity DataIC50: 360nMAssay Description:Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003329BDBM50003329(CHEMBL130188 | (5-{[2-(Acetyl-methyl-amino)-5-guan...)
Affinity DataIC50: 720nMAssay Description:Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003330BDBM50003330(CHEMBL423881 | (5-{[2-(Benzoyl-methyl-amino)-5-gua...)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003326BDBM50003326(CHEMBL420106 | 3-[4-amino(imino)methylamino-1-meth...)
Affinity DataKi:  3.70E+4nMAssay Description:Inhibition of [3H]-107260 binding to purified Fibrinogen receptor of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003326BDBM50003326(CHEMBL420106 | 3-[4-amino(imino)methylamino-1-meth...)
Affinity DataIC50: 9.13E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed