Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50013719
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133761BDBM50133761(3-[5-(3-Trifluoromethyl-phenyl)-1H-imidazol-2-yl]-...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133775BDBM50133775(4-[5-(3,4-Dichloro-phenyl)-1H-imidazol-2-yl]-pyrid...)
Affinity DataKi:  3.5nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133780BDBM50133780(3-[5-(3,4-Dichloro-phenyl)-1H-imidazol-2-yl]-pyrid...)
Affinity DataKi:  4nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133762BDBM50133762(3-[5-(3-Trifluoromethoxy-phenyl)-1H-imidazol-2-yl]...)
Affinity DataKi:  4.90nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133779BDBM50133779(3-[5-(3-Chloro-phenyl)-1H-imidazol-2-yl]-pyridine ...)
Affinity DataKi:  8nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133769BDBM50133769(3-(5-m-Tolyl-1H-imidazol-2-yl)-pyridine | CHEMBL33...)
Affinity DataKi:  14nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133782BDBM50133782(3-[5-(4-Chloro-phenyl)-1H-imidazol-2-yl]-pyridine ...)
Affinity DataKi:  16nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133773BDBM50133773(3-[5-(3-Chloro-phenyl)-4-methyl-1H-imidazol-2-yl]-...)
Affinity DataKi:  19nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133767BDBM50133767(3-[5-(2-Chloro-phenyl)-1H-imidazol-2-yl]-pyridine ...)
Affinity DataKi:  21nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133765BDBM50133765(3-[5-(2-Trifluoromethyl-phenyl)-1H-imidazol-2-yl]-...)
Affinity DataKi:  27nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133783BDBM50133783(2-[5-(3,4-Dichloro-phenyl)-1H-imidazol-2-yl]-pyrid...)
Affinity DataKi:  30nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133778BDBM50133778(2,5-Diphenyl-1H-imidazole | 2,4(5)-Diphenylimidazo...)
Affinity DataKi:  34nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133766BDBM50133766(3-[5-(3,4-Difluoro-phenyl)-1H-imidazol-2-yl]-pyrid...)
Affinity DataKi:  34nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133784BDBM50133784(3-[5-(4-Trifluoromethyl-phenyl)-1H-imidazol-2-yl]-...)
Affinity DataKi:  37nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133776BDBM50133776(2-[5-(3,4-Dichloro-phenyl)-1H-imidazol-2-yl]-pyraz...)
Affinity DataKi:  40nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133759BDBM50133759(3-(5-o-Tolyl-1H-imidazol-2-yl)-pyridine | CHEMBL33...)
Affinity DataKi:  40nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133777BDBM50133777(3-[5-(3-Methoxy-phenyl)-1H-imidazol-2-yl]-pyridine...)
Affinity DataKi:  56nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133785BDBM50133785(3-[5-(4-Chloro-phenyl)-4-methyl-1H-imidazol-2-yl]-...)
Affinity DataKi:  69nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133760BDBM50133760(1-[5-(3,4-Dichloro-phenyl)-1H-imidazol-2-yl]-isoqu...)
Affinity DataKi:  116nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133764BDBM50133764(3-[5-(3,4-Dimethoxy-phenyl)-1H-imidazol-2-yl]-pyri...)
Affinity DataKi:  148nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133781BDBM50133781(3-[5-(4-Trifluoromethoxy-phenyl)-1H-imidazol-2-yl]...)
Affinity DataKi:  210nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133770BDBM50133770(3-(5-Cyclohexyl-1H-imidazol-2-yl)-pyridine | CHEMB...)
Affinity DataKi:  231nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133763BDBM50133763(3-(4-phenyl-1H-imidazol-2-yl)pyridine | 3-(5-Pheny...)
Affinity DataKi:  525nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133786BDBM50133786(2-(5-Phenyl-1H-imidazol-2-yl)-pyridine | CHEMBL325...)
Affinity DataKi:  1.45E+3nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133774BDBM50133774(4-(5-Phenyl-1H-imidazol-2-yl)-pyridine | 4-(4-phen...)
Affinity DataKi:  1.53E+3nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133772BDBM50133772(4-(2-Pyridin-3-yl-3H-imidazol-4-yl)-benzonitrile |...)
Affinity DataKi:  3.00E+3nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133771BDBM50133771(3-[5-(3,4-Dichloro-phenyl)-1H-imidazol-2-yl]-isoqu...)
Affinity DataKi:  4.77E+3nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133768BDBM50133768(3-[5-(3,4-Dichloro-phenyl)-1H-imidazol-2-yl]-quino...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radioligand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed