Compile Data Set for Download or QSAR
maximum 50k data
Found 43 Enz. Inhib. hit(s) with all data for entry = 1173
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9606((2R,3S,4S,5R)-1,6-bis[(2-fluorophenyl)methoxy]-2,5...)
Affinity DataIC50:  200nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9594((2R,3S,4S,5R)-2,5-bis(benzyloxy)-1,6-bis[(2,6-difl...)
Affinity DataIC50:  330nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9605((2R,3S,4S,5R)-1,6-bis[(2,6-difluorophenyl)methoxy]...)
Affinity DataIC50:  330nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9593((2R,3S,4S,5R)-2,5-bis(benzyloxy)-1,6-bis[(2-fluoro...)
Affinity DataIC50:  600nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9576((2R,3S,4S,5R)-1,6-bis(benzyloxy)-2,5-bis[(4-fluoro...)
Affinity DataIC50:  700nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9604((2R,3S,4S,5R)-1,6-bis[(2-fluorophenyl)methoxy]-2,5...)
Affinity DataIC50:  800nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9603((2R,3S,4S,5R)-2,5-bis(benzyloxy)-1,6-bis({[4-(hydr...)
Affinity DataIC50:  1.20E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9592((2R,3S,4S,5R)-2,5-bis(benzyloxy)-1,6-bis[(3-fluoro...)
Affinity DataIC50:  1.50E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9574((2R,3S,4S,5R)-1,2,5,6-tetrakis[(4-fluorophenyl)met...)
Affinity DataIC50:  1.60E+3nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9579((2R,3S,4S,5R)-1,6-bis(benzyloxy)-2,5-bis[(3-fluoro...)
Affinity DataIC50:  1.80E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9601(tetra-O-benzyl-d-mannitol deriv. 1ee)
Affinity DataIC50:  2.00E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9577((2R,3S,4S,5R)-1,6-bis(benzyloxy)-2,5-bis[(4-chloro...)
Affinity DataIC50:  2.00E+3nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9578((2R,3S,4S,5R)-1,6-bis(benzyloxy)-2,5-bis[(4-bromop...)
Affinity DataIC50:  2.10E+3nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9571((2R,3S,4S,5R)-1,2,5,6-tetrakis(benzyloxy)hexane-3,...)
Affinity DataIC50:  2.40E+3nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9591((2R,3S,4S,5R)-2,5-bis(benzyloxy)-1,6-bis[(4-fluoro...)
Affinity DataIC50:  2.50E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9582((2R,3S,4S,5R)-1,6-bis(benzyloxy)-2,5-bis[(2,4-difl...)
Affinity DataIC50:  2.60E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9599((2R,3S,4S,5R)-2,5-bis(benzyloxy)-1,6-bis[(4-methyl...)
Affinity DataIC50:  3.00E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9575(4-({[(2R,3S,4S,5R)-1,5,6-tris[(4-cyanophenyl)metho...)
Affinity DataIC50:  3.10E+3nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9584((2R,3S,4S,5R)-1,6-bis(benzyloxy)-2,5-bis[(4-methyl...)
Affinity DataIC50:  3.70E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9580((2R,3S,4S,5R)-1,6-bis(benzyloxy)-2,5-bis[(2-fluoro...)
Affinity DataIC50:  3.70E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9595((2R,3S,4S,5R)-2,5-bis(benzyloxy)-1,6-bis[(2,4-difl...)
Affinity DataIC50:  4.20E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9600(4-({[(2R,3S,4S,5R)-2,5-bis(benzyloxy)-6-[(4-cyanop...)
Affinity DataIC50:  4.30E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9598((2R,3S,4S,5R)-2,5-bis(benzyloxy)-1,6-bis({[4-(trif...)
Affinity DataIC50:  5.00E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9602(4-({[(2R,3S,4S,5R)-2,5-bis(benzyloxy)-6-[(4-carbox...)
Affinity DataIC50:  5.00E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9597((2R,3S,4S,5R)-2,5-bis(benzyloxy)-1,6-bis[(4-chloro...)
Affinity DataIC50:  5.20E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9585(4-({[(2R,3S,4S,5R)-1,6-bis(benzyloxy)-5-[(4-cyanop...)
Affinity DataIC50:  5.40E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9573((2R,3S,4S,5R)-1,2,5,6-tetrakis({[4-(trifluoromethy...)
Affinity DataIC50:  6.00E+3nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9596((2R,3S,4S,5R)-2,5-bis(benzyloxy)-1,6-bis[(4-bromop...)
Affinity DataIC50:  6.00E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9581((2R,3S,4S,5R)-1,6-bis(benzyloxy)-2,5-bis[(2,6-difl...)
Affinity DataIC50:  6.40E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9572((2R,3S,4S,5R)-1,2,5,6-tetrakis[(4-methylphenyl)met...)
Affinity DataIC50:  7.00E+3nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9586(tetra-O-benzyl-d-mannitol deriv. 1p)
Affinity DataIC50:  8.40E+3nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9583((2R,3S,4S,5R)-1,6-bis(benzyloxy)-2,5-bis({[4-(trif...)
Affinity DataIC50:  1.00E+4nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9588((2R,3S,4S,5R)-1,6-bis(benzyloxy)-2,5-bis({[4-(hydr...)
Affinity DataIC50:  1.00E+4nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9590(4-({[(2R,3S,4S,5R)-1,6-bis(benzyloxy)-5-[(4-carbam...)
Affinity DataIC50:  2.00E+4nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9587(4-({[(2R,3S,4S,5R)-1,6-bis(benzyloxy)-5-[(4-carbox...)
Affinity DataIC50:  2.60E+4nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9589((2R,3S,4S,5R)-2,5-bis({[4-(aminomethyl)phenyl]meth...)
Affinity DataIC50:  2.70E+4nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9564((2S,3R,4R,5S)-1,2,5,6-tetrakis(benzyloxy)hexane-3,...)
Affinity DataIC50: >5.00E+4nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9565((2R,3R,4S,5S)-1,2,5,6-tetrakis(benzyloxy)hexane-3,...)
Affinity DataIC50: >5.00E+4nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9566((2R,3S,4S,5S)-1,2,5,6-tetrakis(benzyloxy)hexane-3,...)
Affinity DataIC50: >5.00E+4nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9567((2R,3R,4S,5R)-1,2,5,6-tetrakis(benzyloxy)hexane-3,...)
Affinity DataIC50: >5.00E+4nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9568((2R,3S,4S,5R)-2,5-bis(benzyloxy)-1,6-diphenoxyhexa...)
Affinity DataIC50: >5.00E+4nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9569((2R,3S,4S,5R)-2,5-bis(benzyloxy)-1,6-diphenylhexan...)
Affinity DataIC50: >5.00E+4nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9570((2R,3S,5S)-1,2,5,6-tetrakis(benzyloxy)hexan-3-ol |...)
Affinity DataIC50: >5.00E+4nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed