Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 50013776
LigandPNGBDBM50134559(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  0.550nMAssay Description:In vitro inhibition of the human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134570(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  0.610nMAssay Description:In vitro inhibition of the human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134563(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  0.620nMAssay Description:In vitro inhibition of the human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134557(3-(4-Cyano-phenylethynyl)-4-[(4-cyano-phenyl)-(3-m...)
Affinity DataIC50:  0.630nMAssay Description:In vitro inhibition of the human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134567(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  0.870nMAssay Description:In vitro inhibition of the human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134558(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  0.900nMAssay Description:In vitro inhibition of the human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134561(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  0.950nMAssay Description:In vitro inhibition of the human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134556(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  0.950nMAssay Description:In vitro inhibition of the human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134555(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibition of the human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134564(6-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  1.10nMAssay Description:In vitro inhibition of the human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134565(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  1.30nMAssay Description:In vitro inhibition of the human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134566(6-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  1.30nMAssay Description:In vitro inhibition of the human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM13379(4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)meth...)
Affinity DataIC50:  1.30nMAssay Description:In vitro inhibition of the human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134562(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  1.40nMAssay Description:In vitro inhibition of the human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134569(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  1.60nMAssay Description:In vitro inhibition of the human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134568(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  1.70nMAssay Description:In vitro inhibition of the human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134571(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  2.90nMAssay Description:In vitro inhibition of the human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134560(3-Biphenyl-4-ylethynyl-4-[(4-cyano-phenyl)-(3-meth...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibition of the human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134570(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  110nMAssay Description:In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide corresponding to the C-ter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134557(3-(4-Cyano-phenylethynyl)-4-[(4-cyano-phenyl)-(3-m...)
Affinity DataIC50:  124nMAssay Description:In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide corresponding to the C-ter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134559(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  150nMAssay Description:In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide corresponding to the C-ter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134564(6-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  150nMAssay Description:In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide corresponding to the C-ter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134558(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  160nMAssay Description:In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide corresponding to the C-ter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134565(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  220nMAssay Description:In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide corresponding to the C-ter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134556(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  310nMAssay Description:In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide corresponding to the C-ter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134563(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  490nMAssay Description:In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide corresponding to the C-ter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134562(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  540nMAssay Description:In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide corresponding to the C-ter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134567(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  845nMAssay Description:In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide corresponding to the C-ter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134555(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  1.30E+3nMAssay Description:In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide corresponding to the C-ter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134568(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  1.60E+3nMAssay Description:In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide corresponding to the C-ter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134561(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  1.80E+3nMAssay Description:In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide corresponding to the C-ter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134569(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  1.80E+3nMAssay Description:In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide corresponding to the C-ter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM13379(4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)meth...)
Affinity DataIC50:  3.50E+3nMAssay Description:In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide corresponding to the C-ter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134566(6-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  9.00E+3nMAssay Description:In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide corresponding to the C-ter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134560(3-Biphenyl-4-ylethynyl-4-[(4-cyano-phenyl)-(3-meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide corresponding to the C-ter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134571(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50:  1.60E+4nMAssay Description:In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide corresponding to the C-ter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed