Compile Data Set for Download or QSAR
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Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 1846
TargetCoagulation factor VII(Human)
Pharmacia

LigandPNGBDBM14497(2-Pyridone 14b | N-[(4-carbamimidoylphenyl)methyl]...)
Affinity DataIC50:  52nMpH: 8.0 T: 22°CAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor VII(Human)
Pharmacia

LigandPNGBDBM14495(2-Pyridone 14a | 3-amino-5-[1-({[(4-carbamimidoylp...)
Affinity DataIC50:  118nMpH: 8.0 T: 22°CAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Pharmacia

LigandPNGBDBM14495(2-Pyridone 14a | 3-amino-5-[1-({[(4-carbamimidoylp...)
Affinity DataIC50: >3.00E+4nMpH: 8.0 T: 22°CAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Pharmacia

LigandPNGBDBM14497(2-Pyridone 14b | N-[(4-carbamimidoylphenyl)methyl]...)
Affinity DataIC50: >3.00E+4nMpH: 8.0 T: 22°CAssay Description:Human Factor Xa and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Pharmacia

LigandPNGBDBM14497(2-Pyridone 14b | N-[(4-carbamimidoylphenyl)methyl]...)
Affinity DataIC50: >3.00E+4nMpH: 8.0 T: 22°CAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Pharmacia

LigandPNGBDBM14495(2-Pyridone 14a | 3-amino-5-[1-({[(4-carbamimidoylp...)
Affinity DataIC50: >3.00E+4nMpH: 8.0 T: 22°CAssay Description:Human Factor Xa and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed