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Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50037208
TargetHistone deacetylase 4(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50134803(5,8-Dimethyl-11-(6-oxiranyl-6-oxo-hexyl)-decahydro...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of Histone deacetylase 4 in mammalian cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 4(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50134799(6-((5S,8S,11S,13aR)-5,8-Dimethyl-4,7,10,13-tetraox...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of Histone deacetylase 4 in mammalian cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2b(Maize)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  7.20nMAssay Description:Inhibitory activity against maize Histone deacetylase 2 at 1 mMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2b(Maize)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  50nMAssay Description:Tested for maize Histone deacetylase 2 inhibitory activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2b(Maize)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50134800((E)-N-Hydroxy-3-[1-methyl-4-((E)-3-oxo-3-o-tolyl-p...)
Affinity DataIC50:  270nMAssay Description:Tested for maize Histone deacetylase 2 inhibitory activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2b(Maize)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50134804((E)-N-Hydroxy-3-[1-methyl-4-((E)-3-oxo-3-phenyl-pr...)
Affinity DataIC50:  280nMAssay Description:Tested for maize Histone deacetylase 2 inhibitory activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 4(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)
Affinity DataIC50:  510nMAssay Description:Inhibition of Histone deacetylase 4 in mammalian cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2b(Maize)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50134802((E)-3-{4-[(E)-3-(2-Chloro-phenyl)-3-oxo-propenyl]-...)
Affinity DataIC50:  5.20E+3nMAssay Description:Tested for maize Histone deacetylase 2 inhibitory activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2b(Maize)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50134795((E)-N-Hydroxy-3-[1-methyl-4-((E)-3-oxo-3-m-tolyl-p...)
Affinity DataIC50:  7.90E+3nMAssay Description:Tested for maize Histone deacetylase 2 inhibitory activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2b(Maize)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50134797((E)-N-Hydroxy-3-[1-methyl-4-((E)-3-oxo-3-p-tolyl-p...)
Affinity DataIC50:  1.02E+4nMAssay Description:Tested for maize Histone deacetylase 2 inhibitory activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2b(Maize)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50134796((E)-3-{4-[(E)-3-(3-Chloro-phenyl)-3-oxo-propenyl]-...)
Affinity DataIC50:  2.42E+4nMAssay Description:Tested for maize Histone deacetylase 2 inhibitory activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2b(Maize)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50134801((E)-3-{4-[(E)-3-(4-Chloro-phenyl)-3-oxo-propenyl]-...)
Affinity DataIC50:  2.52E+4nMAssay Description:Tested for maize Histone deacetylase 2 inhibitory activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50134805(6,9-Dibenzyl-12-(6-oxiranyl-6-oxo-hexyl)-decahydro...)
Affinity DataEC50:  5.24E+5nMAssay Description:Tested for inhibition of Histone deacetylase 6 induced acetylated tubulin in mammalian cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50134805(6,9-Dibenzyl-12-(6-oxiranyl-6-oxo-hexyl)-decahydro...)
Affinity DataEC50:  820nMAssay Description:Inhibition of Histone deacetylase 1 induced acetylated histone in mammalian cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)
Affinity DataEC50:  3.60E+4nMAssay Description:Inhibition of Histone deacetylase 1 induced acetylated histone in mammalian cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50134803(5,8-Dimethyl-11-(6-oxiranyl-6-oxo-hexyl)-decahydro...)
Affinity DataEC50:  3.60E+5nMAssay Description:Tested for inhibition of Histone deacetylase 6 induced acetylated tubulin in mammalian cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM22449(CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...)
Affinity DataEC50:  2.90E+3nMAssay Description:Tested for inhibition of Histone deacetylase 6 induced acetylated tubulin in mammalian cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50134803(5,8-Dimethyl-11-(6-oxiranyl-6-oxo-hexyl)-decahydro...)
Affinity DataEC50:  110nMAssay Description:Inhibition of Histone deacetylase 1 induced acetylated histone in mammalian cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50134799(6-((5S,8S,11S,13aR)-5,8-Dimethyl-4,7,10,13-tetraox...)
Affinity DataEC50:  1.90E+3nMAssay Description:Inhibition of Histone deacetylase 1 induced acetylated histone in mammalian cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50134799(6-((5S,8S,11S,13aR)-5,8-Dimethyl-4,7,10,13-tetraox...)
Affinity DataEC50:  1.90E+4nMAssay Description:Tested for inhibition of Histone deacetylase 6 induced acetylated tubulin in mammalian cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)
Affinity DataEC50:  1.40E+7nMAssay Description:Tested for inhibition of Histone deacetylase 6 induced acetylated tubulin in mammalian cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM22449(CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...)
Affinity DataEC50:  2.17E+5nMAssay Description:Inhibition of Histone deacetylase 1 induced acetylated histone in mammalian cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataEC50:  6.00E+3nMAssay Description:Inhibition of Histone deacetylase 1 induced acetylated histone in mammalian cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed