Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 60 Enz. Inhib. hit(s) with all data for entry = 50013834
TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135254((S)-1-(1H-Indol-4-yloxy)-3-[(1S,3R,5R)-3-(4-methox...)
Affinity DataKi:  0.170nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135249((S)-1-((2S,4R)-4-(5-fluorobenzo[b]thiophen-2-yl)-2...)
Affinity DataKi:  0.240nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135248(4-{(S)-2-Hydroxy-3-[(1R,3S,5S)-3-(4-methoxy-benzo[...)
Affinity DataKi:  0.370nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135244((S)-1-[(2S,4R)-4-(6-Fluoro-benzo[b]thiophen-2-yl)-...)
Affinity DataKi:  0.390nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135253((S)-1-[(1S,3R,5R)-3-(4-Methoxy-benzo[b]thiophen-2-...)
Affinity DataKi:  0.450nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135246((S)-1-((2S,4R)-4-(benzo[b]thiophen-2-yl)-2-methylp...)
Affinity DataKi:  0.530nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135263(4-{(S)-2-Hydroxy-3-[(2S,4R)-4-(4-methoxy-benzo[b]t...)
Affinity DataKi:  0.560nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135238((S)-1-(2-Methyl-1H-indol-4-yloxy)-3-[(2S,4R)-2-met...)
Affinity DataKi:  0.620nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135266((S)-1-[(1R,3S,5S)-3-(4-Methoxy-benzo[b]thiophen-2-...)
Affinity DataKi:  0.690nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135265((S)-1-[(2S,4R)-4-(4-Fluoro-benzo[b]thiophen-2-yl)-...)
Affinity DataKi:  0.75nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135256((S)-1-((2S,4R)-4-(4-methoxybenzo[b]thiophen-2-yl)-...)
Affinity DataKi:  0.860nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135265((S)-1-[(2S,4R)-4-(4-Fluoro-benzo[b]thiophen-2-yl)-...)
Affinity DataKi:  0.920nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135242((S)-1-[(2S,4R)-4-(5-Chloro-benzo[b]thiophen-2-yl)-...)
Affinity DataKi:  1nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135259(4-{(S)-2-Hydroxy-3-[(2R,4S)-4-(4-methoxy-benzo[b]t...)
Affinity DataKi:  1.20nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135237((S)-1-(2-Methyl-1H-indol-4-yloxy)-3-[(2S,4R)-2-met...)
Affinity DataKi:  1.30nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130170((S)-1-(1H-Indol-4-yloxy)-3-[(1R,3S,5S)-3-(4-methox...)
Affinity DataKi:  1.30nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135255((S)-1-[(2S,4R)-4-(7-Fluoro-benzo[b]thiophen-2-yl)-...)
Affinity DataKi:  1.30nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135255((S)-1-[(2S,4R)-4-(7-Fluoro-benzo[b]thiophen-2-yl)-...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135251((S)-1-[(2S,4R)-4-(4,6-Dimethyl-benzo[b]thiophen-2-...)
Affinity DataKi:  2nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135257((S)-1-[(2R,4R)-4-(7-Fluoro-benzo[b]thiophen-2-yl)-...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135261((S)-1-[(2S,4R)-4-(6-Methoxy-benzo[b]thiophen-2-yl)...)
Affinity DataKi:  2.40nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135247((S)-1-[(2S,4R)-4-(4,6-Dimethoxy-benzo[b]thiophen-2...)
Affinity DataKi:  2.80nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135239((S)-1-[(2R,4S)-4-(4-Methoxy-benzo[b]thiophen-2-yl)...)
Affinity DataKi:  3.30nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135258((S)-1-[(2S,4R)-4-(4-Methoxy-benzo[b]thiophen-2-yl)...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135245((S)-1-[(2R,4R)-4-(4-Methoxy-benzo[b]thiophen-2-yl)...)
Affinity DataKi:  4.80nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135249((S)-1-((2S,4R)-4-(5-fluorobenzo[b]thiophen-2-yl)-2...)
Affinity DataKi:  5.70nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135241((S)-1-[(2R,4S)-4-(7-Fluoro-benzo[b]thiophen-2-yl)-...)
Affinity DataKi:  6.10nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135263(4-{(S)-2-Hydroxy-3-[(2S,4R)-4-(4-methoxy-benzo[b]t...)
Affinity DataKi:  6.40nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135252(4-{(S)-2-Hydroxy-3-[(2S,4S)-4-(4-methoxy-benzo[b]t...)
Affinity DataKi:  6.60nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135246((S)-1-((2S,4R)-4-(benzo[b]thiophen-2-yl)-2-methylp...)
Affinity DataKi:  7.10nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135266((S)-1-[(1R,3S,5S)-3-(4-Methoxy-benzo[b]thiophen-2-...)
Affinity DataKi:  9.20nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135240((S)-1-[4-(4-Methoxy-benzo[b]thiophen-2-yl)-2,2-dim...)
Affinity DataKi:  9.40nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135240((S)-1-[4-(4-Methoxy-benzo[b]thiophen-2-yl)-2,2-dim...)
Affinity DataKi:  9.42nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135241((S)-1-[(2R,4S)-4-(7-Fluoro-benzo[b]thiophen-2-yl)-...)
Affinity DataKi:  9.80nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135238((S)-1-(2-Methyl-1H-indol-4-yloxy)-3-[(2S,4R)-2-met...)
Affinity DataKi:  11nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135244((S)-1-[(2S,4R)-4-(6-Fluoro-benzo[b]thiophen-2-yl)-...)
Affinity DataKi:  12nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135248(4-{(S)-2-Hydroxy-3-[(1R,3S,5S)-3-(4-methoxy-benzo[...)
Affinity DataKi:  12nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135264(4-{(S)-2-Hydroxy-3-[(2R,4R)-4-(4-methoxy-benzo[b]t...)
Affinity DataKi:  13nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135261((S)-1-[(2S,4R)-4-(6-Methoxy-benzo[b]thiophen-2-yl)...)
Affinity DataKi:  13nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135256((S)-1-((2S,4R)-4-(4-methoxybenzo[b]thiophen-2-yl)-...)
Affinity DataKi:  14nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135250((S)-1-[(2R,4S)-4-(4-Methoxy-benzo[b]thiophen-2-yl)...)
Affinity DataKi:  15nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135242((S)-1-[(2S,4R)-4-(5-Chloro-benzo[b]thiophen-2-yl)-...)
Affinity DataKi:  16nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135264(4-{(S)-2-Hydroxy-3-[(2R,4R)-4-(4-methoxy-benzo[b]t...)
Affinity DataKi:  16nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130170((S)-1-(1H-Indol-4-yloxy)-3-[(1R,3S,5S)-3-(4-methox...)
Affinity DataKi:  16nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135243((S)-1-[(2S,4S)-4-(7-Fluoro-benzo[b]thiophen-2-yl)-...)
Affinity DataKi:  19nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135260((S)-1-[(2R,4R)-4-(4-Methoxy-benzo[b]thiophen-2-yl)...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135253((S)-1-[(1S,3R,5R)-3-(4-Methoxy-benzo[b]thiophen-2-...)
Affinity DataKi:  21nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135247((S)-1-[(2S,4R)-4-(4,6-Dimethoxy-benzo[b]thiophen-2...)
Affinity DataKi:  23nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135250((S)-1-[(2R,4S)-4-(4-Methoxy-benzo[b]thiophen-2-yl)...)
Affinity DataKi:  27nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135239((S)-1-[(2R,4S)-4-(4-Methoxy-benzo[b]thiophen-2-yl)...)
Affinity DataKi:  28nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Displayed 1 to 50 (of 60 total ) | Next | Last >>
Jump to: