Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50013851
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135430BDBM50135430(Naphthalene-2-carboxylic acid (3R,5S)-1-{(S)-2-[(R...)
Affinity DataKi:  110nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135432BDBM50135432(Naphthalene-2-carboxylic acid (3R,5S)-5-((S)-1-for...)
Affinity DataKi:  400nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135442BDBM50135442((S)-4-Acetylamino-4-[(S)-1-((S)-1-{(S)-1-[(2S,4R)-...)
Affinity DataKi:  890nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135437BDBM50135437(3,4-Dihydro-2H-quinoline-1-carboxylic acid (3R,5S)...)
Affinity DataKi:  890nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135429BDBM50135429(Pyrazine-2-carboxylic acid ((R)-1-{(R)-1-[(2S,4R)-...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135439BDBM50135439(Naphthalene-1-carboxylic acid (3R,5S)-5-((S)-1-for...)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135434BDBM50135434(Pyrazine-2-carboxylic acid ((R)-1-{(R)-1-[(2S,4R)-...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135441BDBM50135441(2-[(3R,5S)-5-((S)-1-Formyl-propylcarbamoyl)-1-((R)...)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135440BDBM50135440(Pyrazine-2-carboxylic acid ((R)-1-{(R)-1-[(2S,4R)-...)
Affinity DataKi:  2.90E+3nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135438BDBM50135438(Pyrazine-2-carboxylic acid ((S)-1-{(S)-1-[(2S,4R)-...)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135443BDBM50135443((2,5-Dichloro-phenyl)-carbamic acid (3R,5S)-5-((S)...)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135447BDBM50135447(Pyrazine-2-carboxylic acid ((S)-1-{(S)-1-[(2S,4R)-...)
Affinity DataKi:  3.80E+3nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135449BDBM50135449(Pyrazine-2-carboxylic acid ((R)-1-{(R)-1-[(2S,4R)-...)
Affinity DataKi:  3.90E+3nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135427BDBM50135427(Benzoic acid (3R,5S)-5-((S)-1-formyl-propylcarbamo...)
Affinity DataKi:  5.80E+3nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135446BDBM50135446(Pyrazine-2-carboxylic acid ((R)-1-{(R)-1-[(2S,4R)-...)
Affinity DataKi:  7.40E+3nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135445BDBM50135445((2,5-Dimethoxy-phenyl)-carbamic acid (3R,5S)-5-((S...)
Affinity DataKi:  7.90E+3nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135428BDBM50135428(Pyrazine-2-carboxylic acid ((R)-1-{(R)-1-[(S)-4-be...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135444BDBM50135444(Pyrazine-2-carboxylic acid ((S)-1-{(S)-1-[(2S,4R)-...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135435BDBM50135435(Naphthalen-1-yl-carbamic acid (3R,5S)-5-((S)-1-for...)
Affinity DataKi:  1.25E+4nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135436BDBM50135436(Phenyl-carbamic acid (3R,5S)-5-((S)-1-formyl-propy...)
Affinity DataKi:  2.23E+4nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135431BDBM50135431(Pyrazine-2-carboxylic acid ((S)-1-{(S)-1-[(2S,4R)-...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135433BDBM50135433(Pyrazine-2-carboxylic acid ((R)-1-{(R)-1-[(2S,4R)-...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135448BDBM50135448(Pyrazine-2-carboxylic acid ((S)-1-{(S)-1-[(2S,4R)-...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of HCV (Hepatitis C Virus) NS3-4A protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed