Compile Data Set for Download or QSAR
maximum 50k data
Found 42 Enz. Inhib. hit(s) with all data for entry = 50035340
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135570(3-(3,4-Dimethoxy-phenyl)-8-methyl-8-aza-bicyclo[3....)
Affinity DataKi:  46nMAssay Description:Ability to inhibit the binding of [125I]RT155 to Serotonin transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)
Affinity DataKi:  297nMAssay Description:Displacement of [125I]RT155 binding in HEK cells expressing human SERTMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)
Affinity DataKi:  419nMAssay Description:Inhibition of [3H]5-HT uptake in HEK cells expressing human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)
Affinity DataKi:  645nMAssay Description:Displacement of [125I]RT155 binding in HEK cells expressing human NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135571(3-(3,4-Diacetyl-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataKi:  704nMAssay Description:Ability to inhibit the binding of [125I]RT155 to hNET in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135571(3-(3,4-Diacetyl-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataKi:  704nMAssay Description:Inhibition of [3H]dopamine uptake in HEK cells expressing human DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135573(3-(3,4-Dihydroxy-phenyl)-8-methyl-8-aza-bicyclo[3....)
Affinity DataKi:  970nMAssay Description:Ability to inhibit the binding of [125I]RT155 to hDAT in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135573(3-(3,4-Dihydroxy-phenyl)-8-methyl-8-aza-bicyclo[3....)
Affinity DataKi:  970nMAssay Description:Inhibition of [3H]dopamine uptake in HEK cells expressing human DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135570(3-(3,4-Dimethoxy-phenyl)-8-methyl-8-aza-bicyclo[3....)
Affinity DataKi:  1.54E+3nMAssay Description:Ability to inhibit the binding of [125I]RT155 to hDAT in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135573(3-(3,4-Dihydroxy-phenyl)-8-methyl-8-aza-bicyclo[3....)
Affinity DataKi:  2.96E+3nMAssay Description:Ability to inhibit the binding of [H]norepinephrine to NE receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135573(3-(3,4-Dihydroxy-phenyl)-8-methyl-8-aza-bicyclo[3....)
Affinity DataKi:  3.06E+3nMAssay Description:Ability to inhibit the binding of [125I]RT155 to hNET in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135570(3-(3,4-Dimethoxy-phenyl)-8-methyl-8-aza-bicyclo[3....)
Affinity DataKi:  4.50E+3nMAssay Description:Ability to inhibit the binding of [125I]RT155 to hNET in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Affinity DataKi:  6.40E+3nMAssay Description:Ability to inhibit the binding of [125I]RT155 to hDAT in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135571(3-(3,4-Diacetyl-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit the binding of [H]norepinephrine to NE receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135569(3-(3,4-Diacetyl-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit the binding of [125I]RT155 to hDAT in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135569(3-(3,4-Diacetyl-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit the binding of [125I]RT155 to Serotonin transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135572(3-(3,4-Dihydroxy-phenyl)-8-methyl-8-aza-bicyclo[3....)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit the binding of [125I]RT155 to hNET in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135572(3-(3,4-Dihydroxy-phenyl)-8-methyl-8-aza-bicyclo[3....)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit the binding of [125I]RT155 to hDAT in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135569(3-(3,4-Diacetyl-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit the binding of [125I]RT155 to hNET in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135571(3-(3,4-Diacetyl-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit the binding of [125I]RT155 to hDAT in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135571(3-(3,4-Diacetyl-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit the binding of [125I]RT155 to hNET in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135572(3-(3,4-Dihydroxy-phenyl)-8-methyl-8-aza-bicyclo[3....)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit the binding of [125I]RT155 to Serotonin transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135571(3-(3,4-Diacetyl-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]RT155 binding in HEK cells expressing human DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135573(3-(3,4-Dihydroxy-phenyl)-8-methyl-8-aza-bicyclo[3....)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of [3H]dopamine uptake in HEK cells expressing human DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135573(3-(3,4-Dihydroxy-phenyl)-8-methyl-8-aza-bicyclo[3....)
Affinity DataKi:  1.00E+4nMAssay Description:Ability to inhibit the binding of [125I]RT155 to Serotonin transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Affinity DataKi: >2.80E+4nMAssay Description:Displacement of [125I]RT155 binding in HEK cells expressing human NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Affinity DataKi: >1.10E+6nMAssay Description:Displacement of [125I]RT155 binding in HEK cells expressing human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Affinity DataIC50:  6.60nMAssay Description:Ability to inhibit the binding of [H]norepinephrine to NE receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135570(3-(3,4-Dimethoxy-phenyl)-8-methyl-8-aza-bicyclo[3....)
Affinity DataIC50:  23nMAssay Description:Inhibition of [3H]5-HT uptake in HEK cells expressing human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135573(3-(3,4-Dihydroxy-phenyl)-8-methyl-8-aza-bicyclo[3....)
Affinity DataIC50:  173nMAssay Description:Ability to inhibit the binding of [H]norepinephrine to NE receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135573(3-(3,4-Dihydroxy-phenyl)-8-methyl-8-aza-bicyclo[3....)
Affinity DataIC50:  173nMAssay Description:Ability to inhibit the binding of [H]norepinephrine to NE receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)
Affinity DataIC50:  192nMAssay Description:Inhibition of [3H]norepinephrine uptake in HEK cells expressing human NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135573(3-(3,4-Dihydroxy-phenyl)-8-methyl-8-aza-bicyclo[3....)
Affinity DataIC50:  308nMAssay Description:Inhibition of [3H]5-HT uptake in HEK cells expressing human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)
Affinity DataIC50:  325nMAssay Description:Inhibition of [3H]dopamine uptake in HEK cells expressing human DATMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135571(3-(3,4-Diacetyl-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataIC50:  330nMAssay Description:Inhibition of [3H]5-HT uptake in HEK cells expressing human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)
Affinity DataIC50:  330nMAssay Description:Inhibition of [3H]dopamine uptake in HEK cells expressing human DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135573(3-(3,4-Dihydroxy-phenyl)-8-methyl-8-aza-bicyclo[3....)
Affinity DataIC50:  406nMAssay Description:Inhibition of [3H]dopamine uptake in HEK cells expressing human DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135573(3-(3,4-Dihydroxy-phenyl)-8-methyl-8-aza-bicyclo[3....)
Affinity DataIC50:  406nMAssay Description:Inhibition of [3H]dopamine uptake in HEK cells expressing human DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Affinity DataIC50:  460nMAssay Description:Inhibition of [3H]dopamine uptake in HEK cells expressing human DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135570(3-(3,4-Dimethoxy-phenyl)-8-methyl-8-aza-bicyclo[3....)
Affinity DataIC50:  1.45E+3nMAssay Description:Ability to inhibit the binding of [H]norepinephrine to NE receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135570(3-(3,4-Dimethoxy-phenyl)-8-methyl-8-aza-bicyclo[3....)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of [3H]norepinephrine uptake in HEK cells expressing human NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of [3H]5-HT uptake in HEK cells expressing human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank