Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50022504
TargetEpidermal growth factor receptor(Human)
Ann Arbor Laboratories

Curated by ChEMBL
LigandPNGBDBM50182685(Canertinib dihydrochloride | CI-1033 | N-[4-(3-Chl...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of purified ErbB1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Ann Arbor Laboratories

Curated by ChEMBL
LigandPNGBDBM50182685(Canertinib dihydrochloride | CI-1033 | N-[4-(3-Chl...)
Affinity DataIC50: 7nMAssay Description:Inhibition of purified ErbB4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Ann Arbor Laboratories

Curated by ChEMBL
LigandPNGBDBM50182685(Canertinib dihydrochloride | CI-1033 | N-[4-(3-Chl...)
Affinity DataIC50: 19nMAssay Description:Inhibition of purified ErbB2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ann Arbor Laboratories

Curated by ChEMBL
LigandPNGBDBM50182685(Canertinib dihydrochloride | CI-1033 | N-[4-(3-Chl...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of purified Pp60Src (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInsulin receptor(Human)
Ann Arbor Laboratories

Curated by ChEMBL
LigandPNGBDBM50182685(Canertinib dihydrochloride | CI-1033 | N-[4-(3-Chl...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of purified INSR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Ann Arbor Laboratories

Curated by ChEMBL
LigandPNGBDBM50182685(Canertinib dihydrochloride | CI-1033 | N-[4-(3-Chl...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of purified CDK1/Cyclin B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Ann Arbor Laboratories

Curated by ChEMBL
LigandPNGBDBM50182685(Canertinib dihydrochloride | CI-1033 | N-[4-(3-Chl...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of purified CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Ann Arbor Laboratories

Curated by ChEMBL
LigandPNGBDBM50182685(Canertinib dihydrochloride | CI-1033 | N-[4-(3-Chl...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of purified PKC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed