Compile Data Set for Download or QSAR
maximum 50k data
Found 31 Enz. Inhib. hit(s) with all data for entry = 50035342
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM16047((4S)-4-[(2S)-2-[(2R,4S,5S)-5-[(2S)-2-[(2S)-2-[(4S)...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136343(CHEMBL137755 | Glu-Val-Asn-statine-Val-Ala-Glu-Phe)
Affinity DataIC50:  46nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136347(CHEMBL335837 | Glu-Val-Met-statine-Val-Ala-Glu-Phe)
Affinity DataIC50:  58nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50366850(CHEMBL1791017)
Affinity DataIC50:  69nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50366842(CHEMBL1791018)
Affinity DataIC50:  86nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50366843(CHEMBL1791010)
Affinity DataIC50:  91nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136339((S)-4-{(S)-2-[(S)-2-((3S,4S)-4-{(S)-2-[(S)-2-((S)-...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136333((S)-4-{(S)-2-[(S)-2-((3S,4S)-4-{(S)-2-[(S)-2-((S)-...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against human brain beta-APP (amyloid precursor protein) cleaving enzyme Beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50366847(CHEMBL1791012)
Affinity DataIC50:  110nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50366851(CHEMBL1791016)
Affinity DataIC50:  130nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136342(CHEMBL134730 | Glu-Val-Met-statine-Leu-Ala-Glu-Phe)
Affinity DataIC50:  140nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50366849(CHEMBL1791011)
Affinity DataIC50:  140nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50366846(CHEMBL1791009)
Affinity DataIC50:  180nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50366848(CHEMBL1791021)
Affinity DataIC50:  220nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50366844(CHEMBL1791020)
Affinity DataIC50:  250nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50366852(CHEMBL1791013)
Affinity DataIC50:  250nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50366841(CHEMBL1791014)
Affinity DataIC50:  260nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136328(3-[((S)-2-{(3S,4S)-4-[(S)-2-((S)-2-Acetylamino-4-m...)
Affinity DataIC50:  520nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136329((S)-4-Amino-4-{(S)-1-[(S)-2-carbamoyl-1-((S)-1-{(S...)
Affinity DataIC50:  530nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136350(3-[((S)-2-{(3S,4S)-4-[(S)-2-((S)-2-Acetylamino-pen...)
Affinity DataIC50:  830nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136334(3-[((S)-2-{(3S,4S)-4-[(S)-2-((S)-2-Acetylamino-4-m...)
Affinity DataIC50:  890nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136348(3-[((S)-2-{(3S,4S)-4-[(S)-2-((S)-2-Acetylamino-hex...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136351((S)-4-[(S)-2-((S)-2-{(3S,4S)-4-[(S)-2-((S)-2-Amino...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136336(3-[((S)-2-{(3S,4S)-4-[(S)-2-((S)-2-Acetylamino-3-m...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136325((S)-4-Amino-4-[(S)-1-((S)-2-carbamoyl-1-{(S)-1-[(S...)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136332((S)-4-Amino-4-((S)-1-{(S)-2-carbamoyl-1-[(S)-1-((S...)
Affinity DataIC50: >9.10E+4nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136335((S)-4-((S)-2-{(S)-2-[(3S,4S)-4-((S)-2-Amino-3-carb...)
Affinity DataIC50: >9.10E+4nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50366845(CHEMBL1791019)
Affinity DataIC50: >9.10E+4nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136354(3-[((R)-2-{(3S,4S)-4-[(S)-2-((S)-2-Acetylamino-4-m...)
Affinity DataIC50: >9.10E+4nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136349(3-[((S)-2-{(3S,4S)-4-[(R)-2-((S)-2-Acetylamino-4-m...)
Affinity DataIC50: >9.10E+4nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136327(3-[((S)-2-{(3S,4S)-4-[(R)-2-((S)-2-Acetylamino-4-m...)
Affinity DataIC50: >9.10E+4nMAssay Description:Inhibition of human beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed