Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50013983
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136661BDBM50136661((R)-2-Amino-1-[(S)-2-(5-propyl-1H-imidazol-2-yl)-2...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136662BDBM50136662((S)-2-Amino-1-[(S)-2-(5-propyl-1H-imidazol-2-yl)-2...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136644BDBM50136644((S)-2-Amino-1-[(S)-5-chloro-2-(5-propyl-1H-imidazo...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136648BDBM50136648((S)-2-Amino-1-[(S)-2-(5-propyl-1H-imidazol-2-yl)-2...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136667BDBM50136667(2-Amino-1-[(S)-5-chloro-2-(5-propyl-1H-imidazol-2-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136645BDBM50136645((S)-2-Amino-1-[(S)-5-methoxy-2-(5-propyl-1H-imidaz...)
Affinity DataIC50: 16nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136654BDBM50136654((S)-2-Amino-3-methyl-1-[(S)-2-(5-propyl-1H-imidazo...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121285BDBM50121285((S)-2-Amino-1-[(S)-2-(5-ethyl-1H-imidazol-2-yl)-2,...)
Affinity DataIC50: 23nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136663BDBM50136663(2-Amino-1-[(S)-2-(5-propyl-1H-imidazol-2-yl)-2,3-d...)
Affinity DataIC50: 36nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136636BDBM50136636(2-Amino-1-[(S)-5-fluoro-2-(5-propyl-1H-imidazol-2-...)
Affinity DataIC50: 46nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136666BDBM50136666(2-Amino-1-[(S)-2-(5-butyl-1H-imidazol-2-yl)-2,3-di...)
Affinity DataIC50: 50nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136656BDBM50136656(2-Amino-1-[(S)-2-(4-methyl-5-propyl-1H-imidazol-2-...)
Affinity DataIC50: 55nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136660BDBM50136660(2-Amino-1-[(S)-5-methoxy-2-(5-propyl-1H-imidazol-2...)
Affinity DataIC50: 70nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136651BDBM50136651(({2-[(S)-1-(2-Amino-acetyl)-2,3-dihydro-1H-indol-2...)
Affinity DataIC50: 135nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136652BDBM50136652(2-Amino-1-[(S)-2-(5-ethyl-1H-imidazol-2-yl)-2,3-di...)
Affinity DataIC50: 194nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136650BDBM50136650(2-[(S)-1-(2-Amino-acetyl)-2,3-dihydro-1H-indol-2-y...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136655BDBM50136655(2-[(S)-1-(2-Amino-acetyl)-2,3-dihydro-1H-indol-2-y...)
Affinity DataIC50: 210nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136637BDBM50136637(2-Amino-1-[(S)-2-(1H-benzoimidazol-2-yl)-2,3-dihyd...)
Affinity DataIC50: 450nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136638BDBM50136638((S)-2-Amino-1-[(S)-2-(5-propyl-1H-imidazol-2-yl)-3...)
Affinity DataIC50: 800nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136638BDBM50136638((S)-2-Amino-1-[(S)-2-(5-propyl-1H-imidazol-2-yl)-3...)
Affinity DataIC50: 800nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136668BDBM50136668((S)-2-Amino-1-[(S)-2-(1H-benzoimidazol-2-yl)-2,3-d...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136658BDBM50136658([(S)-2-(5-Propyl-1H-imidazol-2-yl)-2,3-dihydro-ind...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136665BDBM50136665(2-Amino-1-[(S)-2-(4-ethyl-1-methyl-1H-imidazol-2-y...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136635BDBM50136635(2-Amino-1-[(S)-2-(5-propyl-[1,3,4]oxadiazol-2-yl)-...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136647BDBM50136647((S)-2-Amino-3-phenyl-1-[(S)-2-(5-propyl-1H-imidazo...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136641BDBM50136641(2-Amino-1-[(S)-2-(5-ethyl-thiazol-2-yl)-2,3-dihydr...)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136653BDBM50136653((3-Nitro-phenyl)-[(S)-2-(5-propyl-1H-imidazol-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136639BDBM50136639(3-Amino-1-[(S)-2-(5-propyl-1H-imidazol-2-yl)-2,3-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136664BDBM50136664(2-Amino-1-[(S)-2-(5-propyl-4H-[1,2,4]triazol-3-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136649BDBM50136649((3-Amino-phenyl)-[(S)-2-(5-propyl-1H-imidazol-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136646BDBM50136646(2-Amino-1-[(S)-2-(5-ethyl-1-methyl-1H-imidazol-2-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136657BDBM50136657((2-Nitro-phenyl)-[(S)-2-(5-propyl-1H-imidazol-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136643BDBM50136643((S)-2-[(S)-2-(5-Ethyl-1H-imidazol-2-yl)-2,3-dihydr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136642BDBM50136642((S)-2-Methylamino-1-[(S)-2-(5-propyl-1H-imidazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136669BDBM50136669((1H-Imidazol-4-yl)-[(S)-2-(5-propyl-1H-imidazol-2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136659BDBM50136659(2-Amino-1-[(S)-2-(5-phenyl-1H-imidazol-2-yl)-2,3-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTripeptidyl-peptidase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136640BDBM50136640((2-Amino-phenyl)-[(S)-2-(5-propyl-1H-imidazol-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed