Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50013985
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136685([3-Furan-2-yl-3-(naphthalen-1-yloxy)-propyl]-methy...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to serotonin transporter, using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM84745(DULOXETINE | LY-248686 | CAS_136434-34-9 | LY24868...)
Affinity DataKi:  0.800nMAssay Description:Ability to inhibit the reuptake of 5-HT at human serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136672([3-(4-Fluoro-phenyl)-3-(naphthalen-1-yloxy)-propyl...)
Affinity DataKi:  0.950nMAssay Description:Binding affinity to serotonin transporter, using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136683(Methyl-[3-(naphthalen-1-yloxy)-3-thiophen-3-yl-pro...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to serotonin transporter, using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136680(CHEMBL424660 | N-methyl-3-(1-naphthyloxy)-3-(2-thi...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to serotonin transporter, using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136679(Methyl-[3-(naphthalen-1-yloxy)-3-o-tolyl-propyl]-a...)
Affinity DataKi:  2nMAssay Description:Binding affinity to serotonin transporter, using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136689(Methyl-[3-(naphthalen-1-yloxy)-3-p-tolyl-propyl]-a...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to serotonin transporter, using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136690([3-(3-Methoxy-phenyl)-3-(naphthalen-1-yloxy)-propy...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to serotonin transporter, using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136691([3-(2-Methoxy-phenyl)-3-(naphthalen-1-yloxy)-propy...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to serotonin transporter, using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136682(Methyl-[3-(naphthalen-1-yloxy)-3-phenyl-propyl]-am...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity to serotonin transporter, using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136686([3-(4-Methoxy-phenyl)-3-(naphthalen-1-yloxy)-propy...)
Affinity DataKi:  3.5nMAssay Description:Binding affinity to serotonin transporter, using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136688([3-(4-Chloro-phenyl)-3-(naphthalen-1-yloxy)-propyl...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity to serotonin transporter, using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136675(Methyl-[3-(naphthalen-1-yloxy)-3-m-tolyl-propyl]-a...)
Affinity DataKi:  4nMAssay Description:Binding affinity to serotonin transporter, using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136676([3-(4-Bromo-phenyl)-3-(naphthalen-1-yloxy)-propyl]...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity to serotonin transporter, using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136670(Methyl-[3-(naphthalen-1-yloxy)-3-thiazol-2-yl-prop...)
Affinity DataKi:  6.40nMAssay Description:Binding affinity to serotonin transporter, using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM84745(DULOXETINE | LY-248686 | CAS_136434-34-9 | LY24868...)
Affinity DataKi:  7.5nMAssay Description:Ability to inhibit the reuptake of NE at human norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136678([3-(3-Bromo-phenyl)-3-(naphthalen-1-yloxy)-propyl]...)
Affinity DataKi:  7.60nMAssay Description:Binding affinity to serotonin transporter, using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136677(Methyl-[3-(naphthalen-1-yloxy)-3-(2-trifluoromethy...)
Affinity DataKi:  10nMAssay Description:Binding affinity to serotonin transporter, using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136673(Methyl-[3-(naphthalen-1-yloxy)-3-(4-trifluoromethy...)
Affinity DataKi:  15nMAssay Description:Binding affinity to serotonin transporter, using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136687(Methyl-[3-(naphthalen-1-yloxy)-3-(3-trifluoromethy...)
Affinity DataKi:  19nMAssay Description:Binding affinity to serotonin transporter, using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136682(Methyl-[3-(naphthalen-1-yloxy)-3-phenyl-propyl]-am...)
Affinity DataKi:  20nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136680(CHEMBL424660 | N-methyl-3-(1-naphthyloxy)-3-(2-thi...)
Affinity DataKi:  20nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136685([3-Furan-2-yl-3-(naphthalen-1-yloxy)-propyl]-methy...)
Affinity DataKi:  20nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136683(Methyl-[3-(naphthalen-1-yloxy)-3-thiophen-3-yl-pro...)
Affinity DataKi:  21nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136684(Methyl-[4-(naphthalen-1-yloxy)-butyl]-amine | CHEM...)
Affinity DataKi:  31nMAssay Description:Binding affinity to serotonin transporter, using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136689(Methyl-[3-(naphthalen-1-yloxy)-3-p-tolyl-propyl]-a...)
Affinity DataKi:  36nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136675(Methyl-[3-(naphthalen-1-yloxy)-3-m-tolyl-propyl]-a...)
Affinity DataKi:  40nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136672([3-(4-Fluoro-phenyl)-3-(naphthalen-1-yloxy)-propyl...)
Affinity DataKi:  42nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136670(Methyl-[3-(naphthalen-1-yloxy)-3-thiazol-2-yl-prop...)
Affinity DataKi:  55nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136678([3-(3-Bromo-phenyl)-3-(naphthalen-1-yloxy)-propyl]...)
Affinity DataKi:  67nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136687(Methyl-[3-(naphthalen-1-yloxy)-3-(3-trifluoromethy...)
Affinity DataKi:  70nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136686([3-(4-Methoxy-phenyl)-3-(naphthalen-1-yloxy)-propy...)
Affinity DataKi:  74nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136681(Methyl-[3-(naphthalen-1-yloxy)-propyl]-amine | CHE...)
Affinity DataKi:  75nMAssay Description:Binding affinity to serotonin transporter, using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136688([3-(4-Chloro-phenyl)-3-(naphthalen-1-yloxy)-propyl...)
Affinity DataKi:  78nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136690([3-(3-Methoxy-phenyl)-3-(naphthalen-1-yloxy)-propy...)
Affinity DataKi:  81nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136679(Methyl-[3-(naphthalen-1-yloxy)-3-o-tolyl-propyl]-a...)
Affinity DataKi:  110nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136676([3-(4-Bromo-phenyl)-3-(naphthalen-1-yloxy)-propyl]...)
Affinity DataKi:  160nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM84745(DULOXETINE | LY-248686 | CAS_136434-34-9 | LY24868...)
Affinity DataKi:  240nMAssay Description:Ability to inhibit the reuptake of dopamine at human dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed