Compile Data Set for Download or QSAR
maximum 50k data
Found 58 Enz. Inhib. hit(s) with all data for entry = 50013988
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136699((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50:  25nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136711((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50:  28nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136714((S)-3,5-dichloro-N-(1-(6,7-dimethoxy-3,4-dihydrois...)
Affinity DataIC50:  30nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136718((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50:  35nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136720(CHEMBL343551 | N-[1-Benzyl-2-(6,7-dimethoxy-3,4-di...)
Affinity DataIC50:  36nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136694((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50:  40nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136693((+/-)-2-benzyl-1-(6,7-dimethoxy-3,4-dihydroisoquin...)
Affinity DataIC50:  56nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136701((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50:  59nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136703((+/-)-3-bromo-N-(1-(6,7-dimethoxy-3,4-dihydroisoqu...)
Affinity DataIC50:  70nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136698((S)-2-(benzylamino)-1-(6,7-dimethoxy-3,4-dihydrois...)
Affinity DataIC50:  130nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136710((S)-N-(1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1...)
Affinity DataIC50:  195nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136719((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50:  240nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136702((+/-)-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H...)
Affinity DataIC50:  395nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136705((+/-)-N-(1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2...)
Affinity DataIC50:  900nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136708((+/-)-2-(benzylamino)-1-(6,7-dimethoxy-3,4-dihydro...)
Affinity DataIC50:  910nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136699((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50:  1.13E+3nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136695((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136717((+/-)-2-(4-bromobenzyl)-1-(6,7-dimethoxy-3,4-dihyd...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136704((+/-)-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136714((S)-3,5-dichloro-N-(1-(6,7-dimethoxy-3,4-dihydrois...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136707((R)-2-(benzylamino)-1-(6,7-dimethoxy-3,4-dihydrois...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136697(2-Benzylamino-1-(6,7-dimethoxy-3,4-dihydro-1H-isoq...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136711((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136718((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50:  3.67E+3nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136698((S)-2-(benzylamino)-1-(6,7-dimethoxy-3,4-dihydrois...)
Affinity DataIC50:  3.85E+3nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136720(CHEMBL343551 | N-[1-Benzyl-2-(6,7-dimethoxy-3,4-di...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136693((+/-)-2-benzyl-1-(6,7-dimethoxy-3,4-dihydroisoquin...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136703((+/-)-3-bromo-N-(1-(6,7-dimethoxy-3,4-dihydroisoqu...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136717((+/-)-2-(4-bromobenzyl)-1-(6,7-dimethoxy-3,4-dihyd...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136719((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136696((+/-)-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136706((S)-2-(benzylamino)-1-(6,7-dimethoxy-3,4-dihydrois...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136715((+/-)-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136716((S)-2-Benzylamino-1-(6,7-dimethoxy-3,4-dihydro-1H-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136715((+/-)-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136713((+/-)-2-amino-1-(6,7-dimethoxy-3,4-dihydroisoquino...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136707((R)-2-(benzylamino)-1-(6,7-dimethoxy-3,4-dihydrois...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136712((+/-)-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136710((S)-N-(1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136709((+/-)-N-(1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136712((+/-)-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136705((+/-)-N-(1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136709((+/-)-N-(1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136713((+/-)-2-amino-1-(6,7-dimethoxy-3,4-dihydroisoquino...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136700((+/-)-2-(cyclohexylmethylamino)-1-(6,7-dimethoxy-3...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136708((+/-)-2-(benzylamino)-1-(6,7-dimethoxy-3,4-dihydro...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136704((+/-)-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136706((S)-2-(benzylamino)-1-(6,7-dimethoxy-3,4-dihydrois...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136702((+/-)-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136701((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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