Compile Data Set for Download or QSAR
maximum 50k data
Found 45 Enz. Inhib. hit(s) with all data for entry = 50014132
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138590(2-(7-Hydroxy-3,4-dihydro-1H-isoquinolin-2-ylmethyl...)
Affinity DataIC50:  24nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138578(2-(7-Hydroxy-1-methyl-3,4-dihydro-1H-isoquinolin-2...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138594(2-(5-Hydroxy-1,3-dihydro-isoindol-2-ylmethyl)-N-(4...)
Affinity DataIC50:  33nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138558(2-[(6-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-ylam...)
Affinity DataIC50:  43nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138584(2-{[2-(4-Hydroxy-phenyl)-ethylamino]-methyl}-N-((E...)
Affinity DataIC50:  56nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138559(2-(7-Hydroxy-1,2,4,5-tetrahydro-benzo[d]azepin-3-y...)
Affinity DataIC50:  58nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138556(2-(7-Hydroxy-3-methyl-3,4-dihydro-1H-isoquinolin-2...)
Affinity DataIC50:  67nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138565(CHEMBL348200 | N-[4-(4-Chloro-phenyl)-butyl]-2-{[2...)
Affinity DataIC50:  77nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138555(2-[(6-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-ylam...)
Affinity DataIC50:  81nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138561(2-{[2-(4-Hydroxy-phenyl)-ethylamino]-methyl}-N-(4-...)
Affinity DataIC50:  86nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138569(2-(7-Hydroxy-3,4-dihydro-1H-isoquinolin-2-ylmethyl...)
Affinity DataIC50:  89nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138572(CHEMBL153410 | N-[4-(3-Chloro-phenyl)-butyl]-2-{[2...)
Affinity DataIC50:  99nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138587(CHEMBL348211 | N-[4-(3,4-Dichloro-phenyl)-butyl]-2...)
Affinity DataIC50:  120nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138592(2-(6-Hydroxy-3,4-dihydro-1H-isoquinolin-2-ylmethyl...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138576(2-{[2-(4-Hydroxy-phenyl)-ethylamino]-methyl}-N-[4-...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138575(2-[(2-Hydroxy-6,7,8,9-tetrahydro-5H-benzocyclohept...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138562(2-{[2-(4-Hydroxy-phenyl)-ethylamino]-methyl}-N-[4-...)
Affinity DataIC50:  140nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138564(2-{[2-(4-Hydroxy-phenyl)-ethylamino]-methyl}-N-(4-...)
Affinity DataIC50:  140nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138596(2-{[2-(4-Hydroxy-phenyl)-ethylamino]-methyl}-N-(4-...)
Affinity DataIC50:  170nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138586(2-{[2-(4-Hydroxy-phenyl)-ethylamino]-methyl}-N-((Z...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138579(2-(7-Hydroxy-1,3,4,5-tetrahydro-benzo[c]azepin-2-y...)
Affinity DataIC50:  320nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138566(2-{[2-(3-Hydroxy-phenyl)-ethylamino]-methyl}-N-(4-...)
Affinity DataIC50:  330nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138554(2-{[2-(4-Hydroxy-phenyl)-ethylamino]-methyl}-N-[4-...)
Affinity DataIC50:  370nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138577(2-{[3-(4-Hydroxy-phenyl)-propylamino]-methyl}-N-(4...)
Affinity DataIC50:  670nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138589(2-[(4-Hydroxy-benzylamino)-methyl]-N-(4-phenyl-but...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138585(2-{[2-(2-Hydroxy-phenyl)-ethylamino]-methyl}-N-(4-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138567(2-{[2-(4-Methoxy-phenyl)-ethylamino]-methyl}-N-(4-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50404282(CHEMBL2112891)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138557(2-({[2-(4-Hydroxy-phenyl)-ethyl]-methyl-amino}-met...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138591(2-{[2-(4-Hydroxy-phenyl)-ethylamino]-methyl}-N-(3-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138583(2-[(4-Methoxy-benzylamino)-methyl]-N-(4-phenyl-but...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138593(2-(8-Hydroxy-1,3,4,5-tetrahydro-benzo[c]azepin-2-y...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138552(CHEMBL150409 | N-[4-(4-Hydroxy-phenyl)-butyl]-2-{[...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138573(2-{[2-(4-Fluoro-phenyl)-ethylamino]-methyl}-N-(4-p...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138563(2-[(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-ylam...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138582(2-{[2-(4-Amino-phenyl)-ethylamino]-methyl}-N-(4-ph...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138553(CHEMBL421793 | N-(4-Phenyl-butyl)-2-{[2-(4-trifluo...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138570(2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-1-ylam...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138560(2-{[2-(4-Hydroxy-phenyl)-ethylamino]-methyl}-N-[3-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138588(CHEMBL150722 | N-Benzyl-2-{[2-(4-hydroxy-phenyl)-e...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138581(2-[(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-1-ylam...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138595(2-{[2-(4-Hydroxy-phenyl)-ethylamino]-methyl}-N-phe...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138571(2-{[2-(4-Hydroxy-phenyl)-ethylamino]-methyl}-N-(3-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138574(3-[(4-Methoxy-benzylamino)-methyl]-N-(4-phenyl-but...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138580(2-{[2-(4-Hydroxy-phenyl)-ethylamino]-methyl}-N-met...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed