Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 4250 Sort by
TargetThymidylate synthase(Human)
UniversitÀ

LigandPNGBDBM18771(CHEMBL389051 | (2S)-2-[(4-{[(2-amino-4-oxo-1,4-dih...)
Affinity DataKi:  30nM ΔG°:  -42.2kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Escherichia coli (strain K12))
UniversitÀ

LigandPNGBDBM18771(CHEMBL389051 | (2S)-2-[(4-{[(2-amino-4-oxo-1,4-dih...)
Affinity DataKi:  60nM ΔG°:  -40.5kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
UniversitÀ

LigandPNGBDBM18771(CHEMBL389051 | (2S)-2-[(4-{[(2-amino-4-oxo-1,4-dih...)
Affinity DataKi:  60nM ΔG°:  -40.5kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM18771(CHEMBL389051 | (2S)-2-[(4-{[(2-amino-4-oxo-1,4-dih...)
Affinity DataKi:  80nM ΔG°:  -39.8kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Pneumocystis carinii)
UniversitÀ

LigandPNGBDBM18771(CHEMBL389051 | (2S)-2-[(4-{[(2-amino-4-oxo-1,4-dih...)
Affinity DataKi:  240nM ΔG°:  -37.2kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Escherichia coli (strain K12))
UniversitÀ

LigandPNGBDBM18763(CHEMBL67116 | 4,4-bis(3-chloro-4-hydroxyphenyl)-3-...)
Affinity DataKi:  600nM ΔG°:  -34.9kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Escherichia coli (strain K12))
UniversitÀ

LigandPNGBDBM18763(CHEMBL67116 | 4,4-bis(3-chloro-4-hydroxyphenyl)-3-...)
Affinity DataKi:  700nM ΔG°:  -34.5kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
UniversitÀ

LigandPNGBDBM18772(Phenolnaphthalein derivative, 2 | 4,4-bis(3-bromo-...)
Affinity DataKi:  800nM ΔG°:  -34.2kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidylate synthase(Escherichia coli (strain K12))
UniversitÀ

LigandPNGBDBM18758(Phenolnaphthalein derivative, 4 | 3,3-bis(3-bromo-...)
Affinity DataKi:  900nM ΔG°:  -33.9kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidylate synthase(Escherichia coli (strain K12))
UniversitÀ

LigandPNGBDBM18769(Phenolnaphthalein derivative, 1 | CHEMBL303171 | 4...)
Affinity DataKi:  1.10E+3nM ΔG°:  -33.4kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Escherichia coli (strain K12))
UniversitÀ

LigandPNGBDBM18770(Phenolnaphthalein derivative, 3 | 8-chloro-4,4-bis...)
Affinity DataKi:  1.10E+3nM ΔG°:  -33.4kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
UniversitÀ

LigandPNGBDBM18769(Phenolnaphthalein derivative, 1 | CHEMBL303171 | 4...)
Affinity DataKi:  1.60E+3nM ΔG°:  -32.5kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
UniversitÀ

LigandPNGBDBM18759(Phenolnaphthalein derivative, 5 | 3,3-bis(3,5-dibr...)
Affinity DataKi:  1.70E+3nM ΔG°:  -32.4kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
UniversitÀ

LigandPNGBDBM18770(Phenolnaphthalein derivative, 3 | 8-chloro-4,4-bis...)
Affinity DataKi:  1.80E+3nM ΔG°:  -32.2kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidylate synthase(Escherichia coli (strain K12))
UniversitÀ

LigandPNGBDBM18772(Phenolnaphthalein derivative, 2 | 4,4-bis(3-bromo-...)
Affinity DataKi:  4.10E+3nM ΔG°:  -30.2kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
UniversitÀ

LigandPNGBDBM18758(Phenolnaphthalein derivative, 4 | 3,3-bis(3-bromo-...)
Affinity DataKi:  6.60E+3nM ΔG°:  -29.1kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidylate synthase(Escherichia coli (strain K12))
UniversitÀ

LigandPNGBDBM18759(Phenolnaphthalein derivative, 5 | 3,3-bis(3,5-dibr...)
Affinity DataKi:  8.50E+3nM ΔG°:  -28.5kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidylate synthase(Pneumocystis carinii)
UniversitÀ

LigandPNGBDBM18763(CHEMBL67116 | 4,4-bis(3-chloro-4-hydroxyphenyl)-3-...)
Affinity DataKi:  1.30E+4nM ΔG°:  -27.4kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Pneumocystis carinii)
UniversitÀ

LigandPNGBDBM18770(Phenolnaphthalein derivative, 3 | 8-chloro-4,4-bis...)
Affinity DataKi:  2.20E+4nM ΔG°:  -26.1kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidylate synthase(Pneumocystis carinii)
UniversitÀ

LigandPNGBDBM18772(Phenolnaphthalein derivative, 2 | 4,4-bis(3-bromo-...)
Affinity DataKi:  2.80E+4nM ΔG°:  -25.6kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
UniversitÀ

LigandPNGBDBM18763(CHEMBL67116 | 4,4-bis(3-chloro-4-hydroxyphenyl)-3-...)
Affinity DataKi:  3.00E+4nM ΔG°:  -25.4kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Pneumocystis carinii)
UniversitÀ

LigandPNGBDBM18759(Phenolnaphthalein derivative, 5 | 3,3-bis(3,5-dibr...)
Affinity DataKi:  3.27E+4nM ΔG°:  -25.2kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM18759(Phenolnaphthalein derivative, 5 | 3,3-bis(3,5-dibr...)
Affinity DataKi:  4.10E+4nM ΔG°:  -24.6kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM18758(Phenolnaphthalein derivative, 4 | 3,3-bis(3-bromo-...)
Affinity DataKi:  6.30E+4nM ΔG°:  -23.6kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
UniversitÀ

LigandPNGBDBM18758(Phenolnaphthalein derivative, 4 | 3,3-bis(3-bromo-...)
Affinity DataKi: >1.32E+5nM ΔG°: >-21.8kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidylate synthase(Pneumocystis carinii)
UniversitÀ

LigandPNGBDBM18758(Phenolnaphthalein derivative, 4 | 3,3-bis(3-bromo-...)
Affinity DataKi: >1.32E+5nM ΔG°: >-21.8kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
UniversitÀ

LigandPNGBDBM18770(Phenolnaphthalein derivative, 3 | 8-chloro-4,4-bis...)
Affinity DataKi: >2.45E+5nM ΔG°: >-20.3kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
UniversitÀ

LigandPNGBDBM18772(Phenolnaphthalein derivative, 2 | 4,4-bis(3-bromo-...)
Affinity DataKi: >2.45E+5nM ΔG°: >-20.3kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
UniversitÀ

LigandPNGBDBM18759(Phenolnaphthalein derivative, 5 | 3,3-bis(3,5-dibr...)
Affinity DataKi: >2.45E+5nM ΔG°: >-20.3kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThymidylate synthase(Pneumocystis carinii)
UniversitÀ

LigandPNGBDBM18769(Phenolnaphthalein derivative, 1 | CHEMBL303171 | 4...)
Affinity DataKi: >4.02E+5nM ΔG°: >-19.1kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
UniversitÀ

LigandPNGBDBM18769(Phenolnaphthalein derivative, 1 | CHEMBL303171 | 4...)
Affinity DataKi: >4.02E+5nM ΔG°: >-19.1kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM18763(CHEMBL67116 | 4,4-bis(3-chloro-4-hydroxyphenyl)-3-...)
Affinity DataKi: >1.08E+6nM ΔG°: >-16.6kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM18769(Phenolnaphthalein derivative, 1 | CHEMBL303171 | 4...)
Affinity DataKi: >1.78E+6nM ΔG°: >-15.4kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM18770(Phenolnaphthalein derivative, 3 | 8-chloro-4,4-bis...)
Affinity DataKi: >1.08E+6nM ΔG°: >-16.6kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM18772(Phenolnaphthalein derivative, 2 | 4,4-bis(3-bromo-...)
Affinity DataKi: >1.08E+6nM ΔG°: >-16.6kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed