Compile Data Set for Download or QSAR
maximum 50k data
Found 27 Enz. Inhib. hit(s) with all data for entry = 50014202
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50084655(CHEMBL92708 | Calpeptin | Z-Leu-Nle-CHO | [(S)-1-(...)
Affinity DataIC50:  0.110nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139490(2,2,4,4-tetramethylpentan-3-yl(S)-1,2-dioxo-1-((R)...)
Affinity DataIC50:  0.710nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139481((R)-2,2-dimethyl-6-phenylhexan-3-yl(S)-1,2-dioxo-1...)
Affinity DataIC50:  0.790nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139496((R)-4,4-dimethyl-1-phenylpentan-3-yl(S)-1,2-dioxo-...)
Affinity DataIC50:  1.10nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138842(2,4-dimethylpentan-3-yl(S)-1,2-dioxo-1-((R)-1-phen...)
Affinity DataIC50:  2.5nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139492(CHEMBL355138 | [(S)-1-((R)-1-Phenyl-ethylaminooxal...)
Affinity DataIC50:  6.30nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138842(2,4-dimethylpentan-3-yl(S)-1,2-dioxo-1-((R)-1-phen...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity of the compound against rat cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139497(3,3-dimethylbutan-2-yl(S)-1,2-dioxo-1-((R)-1-pheny...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139485(CHEMBL162041 | [(S)-1-((R)-1-Phenyl-ethylaminooxal...)
Affinity DataIC50:  32nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139487(CHEMBL163185 | [(S)-1-((R)-1-Phenyl-ethylaminooxal...)
Affinity DataIC50:  34nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50137790(((S)-1-Formyl-pentyl)-carbamic acid tert-butyl est...)
Affinity DataIC50:  51nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139483(CHEMBL163757 | [(S)-1-((R)-1-Phenyl-ethylaminooxal...)
Affinity DataIC50:  69nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139499(CHEMBL351877 | [(S)-1-((R)-1-Phenyl-ethylaminooxal...)
Affinity DataIC50:  76nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139493((S)-4,4-dimethyl-1-phenylpentan-3-yl(S)-1,2-dioxo-...)
Affinity DataIC50:  912nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139484(CHEMBL162812 | [(S)-1-((R)-1-Phenyl-ethylaminooxal...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139498(CHEMBL163240 | [(S)-1-((R)-1-Phenyl-ethylaminooxal...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139495(((S)-1-Benzylaminooxalyl-pentyl)-carbamic acid ter...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139480((S)-tert-butyl 1,2-dioxo-1-(thiophen-2-ylmethylami...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139489(CHEMBL163555 | [(S)-1-((S)-1-Phenyl-ethylaminooxal...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139486(((S)-1-Phenethylaminooxalyl-pentyl)-carbamic acid ...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139500(((S)-1-Aminooxalyl-pentyl)-carbamic acid tert-buty...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139491(((S)-1-Phenylaminooxalyl-pentyl)-carbamic acid ter...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139482(((S)-1-Isopropylaminooxalyl-pentyl)-carbamic acid ...)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139494(((S)-1-Ethylaminooxalyl-pentyl)-carbamic acid tert...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139479(((S)-1-Methylaminooxalyl-pentyl)-carbamic acid ter...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139488(CHEMBL165345 | {(S)-1-[Methyl-((R)-1-phenyl-ethyl)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50139501(((S)-1-tert-Butylaminooxalyl-pentyl)-carbamic acid...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed