Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50014215
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139601BDBM50139601(1-(4-bromo-3-(trifluoromethyl)phenyl)-3-(4-(2-(met...)
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16673BDBM16673(BAY439006 | CHEMBL1336 | BAY 43-9006 | 4-[4-({[4-c...)
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139614BDBM50139614(4-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139618BDBM50139618(4-{4-[3-(4-Bromo-3-trifluoromethyl-phenyl)-ureido]...)
Affinity DataIC50: 27nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139621BDBM50139621(4-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-pheno...)
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139626BDBM50139626(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)
Affinity DataIC50: 44nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139620BDBM50139620(5-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139597BDBM50139597(4-{4-[3-(2-Methoxy-5-trifluoromethyl-phenyl)-ureid...)
Affinity DataIC50: 53nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139623BDBM50139623(4-{4-[3-(4-Bromo-3-trifluoromethyl-phenyl)-ureido]...)
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139627BDBM50139627(1-(2-methoxy-5-(trifluoromethyl)phenyl)-3-(4-(5-(m...)
Affinity DataIC50: 61nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139602BDBM50139602(5-{4-[3-(2-Methoxy-5-trifluoromethyl-phenyl)-ureid...)
Affinity DataIC50: 63nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139598BDBM50139598(3-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-pheno...)
Affinity DataIC50: 68nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139635BDBM50139635(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)
Affinity DataIC50: 70nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139596BDBM50139596(4-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)
Affinity DataIC50: 73nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139628BDBM50139628(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)
Affinity DataIC50: 82nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139611BDBM50139611(3-{4-[3-(2-Methoxy-5-trifluoromethyl-phenyl)-ureid...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139606BDBM50139606(N-(2-Dimethylamino-ethyl)-5-{4-[3-(2-methoxy-5-tri...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139629BDBM50139629(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139609BDBM50139609(3-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-pheno...)
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139636BDBM50139636(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139612BDBM50139612(3-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-pheno...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139605BDBM50139605(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139617BDBM50139617(3-{4-[3-(2-Methoxy-5-trifluoromethyl-phenyl)-ureid...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139599BDBM50139599(5-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139613BDBM50139613(3-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-pheno...)
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139608BDBM50139608(N-(6-Methoxy-pyridin-3-yl)-3-{4-[3-(2-methoxy-5-tr...)
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139630BDBM50139630(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139622BDBM50139622(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139624BDBM50139624(4-{4-[3-(4-Bromo-3-trifluoromethyl-phenyl)-ureido]...)
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139625BDBM50139625(3-{4-[3-(2-Methoxy-5-trifluoromethyl-phenyl)-ureid...)
Affinity DataIC50: 210nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139607BDBM50139607(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139604BDBM50139604(1-(5-tert-Butyl-isoxazol-3-yl)-3-[4-(pyridin-4-ylo...)
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139632BDBM50139632(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)
Affinity DataIC50: 270nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139610BDBM50139610(4-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139631BDBM50139631(4-{4-[3-(2-Methoxy-5-trifluoromethyl-phenyl)-ureid...)
Affinity DataIC50: 330nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139619BDBM50139619(3-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-pheno...)
Affinity DataIC50: 370nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139600BDBM50139600(N-(4-Dimethylamino-phenyl)-3-{4-[3-(2-methoxy-5-tr...)
Affinity DataIC50: 410nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139603BDBM50139603(N-Benzyl-3-{4-[3-(5-tert-butyl-isoxazol-3-yl)-urei...)
Affinity DataIC50: 460nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139633BDBM50139633(4-{4-[3-(2-Methoxy-5-trifluoromethyl-phenyl)-ureid...)
Affinity DataIC50: 460nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139615BDBM50139615(4-{4-[3-(2-Methoxy-5-trifluoromethyl-phenyl)-ureid...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105619BDBM50105619(1-(5-tert-butylisoxazol-3-yl)-3-(4-phenoxyphenyl)u...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139634BDBM50139634(4-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139616BDBM50139616(3-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-pheno...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed