Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 716
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 5307BDBM5307(1-methanesulfonyl-4-[(4-{3-phenylimidazo[1,2-a]pyr...)
Affinity DataIC50: 13nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 5308BDBM5308(4-{3-phenylimidazo[1,2-a]pyridin-7-yl}-1-[3-(piper...)
Affinity DataIC50: 28nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 5301BDBM5301(2-{7-phenylimidazo[1,2-a]pyridin-3-yl}-1,3-thiazol...)
Affinity DataIC50: 42nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 5303BDBM5303(4-{7-phenylimidazo[1,2-a]pyridin-3-yl}-1,2-thiazol...)
Affinity DataIC50: 50nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 5305BDBM5305(N-methyl-4-[(4-{3-phenylimidazo[1,2-a]pyridin-7-yl...)
Affinity DataIC50: 52nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 5311BDBM5311(1-(3-{3-[(dimethylamino)methyl]piperidin-1-yl}prop...)
Affinity DataIC50: 67nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 5306BDBM5306(4-[(4-{3-phenylimidazo[1,2-a]pyridin-7-yl}phenyl)m...)
Affinity DataIC50: 69nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 5294BDBM5294(dorsomorphin (6LP) | 6-(4-methoxyphenyl)-3-phenylp...)
Affinity DataIC50: 71nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 5304BDBM5304(1-{4-[(4-{3-phenylimidazo[1,2-a]pyridin-7-yl}pheny...)
Affinity DataIC50: 77nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 5310BDBM5310(1-{3-[(2-methoxyethyl)(methyl)amino]propyl}-4-{3-p...)
Affinity DataIC50: 96nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 5296BDBM5296(3,7-diphenylimidazo[1,2-a]pyridine | imidazopyridi...)
Affinity DataIC50: 98nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 5302BDBM5302(5-{7-phenylimidazo[1,2-a]pyridin-3-yl}-1,3-thiazol...)
Affinity DataIC50: 99nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 5295BDBM5295(5-(4-methoxyphenyl)-1-phenyl-1H-1,3-benzodiazole |...)
Affinity DataIC50: 113nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 5309BDBM5309(1-(3-hydroxypropyl)-4-{3-phenylimidazo[1,2-a]pyrid...)
Affinity DataIC50: 120nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 5297BDBM5297(4-{7-phenylimidazo[1,2-a]pyridin-3-yl}pyridine | i...)
Affinity DataIC50: 145nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 5299BDBM5299(2-methoxy-6-{7-phenylimidazo[1,2-a]pyridin-3-yl}py...)
Affinity DataIC50: 242nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 5298BDBM5298(3-{7-phenylimidazo[1,2-a]pyridin-3-yl}pyridine | i...)
Affinity DataIC50: 930nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 5300BDBM5300(2-methoxy-5-{7-phenylimidazo[1,2-a]pyridin-3-yl}py...)
Affinity DataIC50: 2.84E+3nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed