Compile Data Set for Download or QSAR
maximum 50k data
Found 54 Enz. Inhib. hit(s) with all data for entry = 50014394
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142042((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50:  8nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142047((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50:  15nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142043((2S)-3-(5-(carboxymethoxy)-1H-indol-3-yl)-2-(1-cyc...)
Affinity DataIC50:  19nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142041(3-{(S)-2-Carboxy-2-[(1-cyclohexyl-2-furan-3-yl-1H-...)
Affinity DataIC50:  20nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142056((S)-3-(5-Carbamoyl-1H-indol-3-yl)-2-[(1-cyclohexyl...)
Affinity DataIC50:  37nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142052((2S)-2-(1-cyclohexyl-2-(furan-3-yl)-1H-benzo[d]imi...)
Affinity DataIC50:  50nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142045((S)-3-(5-Acetylamino-1H-indol-3-yl)-2-[(1-cyclohex...)
Affinity DataIC50:  60nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142053((S)-3-(5-Amino-1H-indol-3-yl)-2-[(1-cyclohexyl-2-f...)
Affinity DataIC50:  90nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142044((S)-3-[5-(1-Carboxy-1-methyl-ethoxy)-1H-indol-3-yl...)
Affinity DataIC50:  100nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142049((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50:  120nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142050((S)-2-(1-cyclohexyl-2-(pyridin-2-yl)-1H-benzo[d]im...)
Affinity DataIC50:  140nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142048((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50:  150nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142069((R)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50:  160nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142064((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50:  400nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142051((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50:  400nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142061((2S)-2-(1-cyclohexyl-2-(furan-3-yl)-1H-benzo[d]imi...)
Affinity DataIC50:  400nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142065(CHEMBL177283 | [(1-Cyclohexyl-2-furan-3-yl-1H-benz...)
Affinity DataIC50:  400nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142057(2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazole-5-...)
Affinity DataIC50:  460nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142062((R)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50:  700nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142070((S)-2-[(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidaz...)
Affinity DataIC50:  1.50E+3nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142063(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazole-5-carb...)
Affinity DataIC50:  1.50E+3nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137488(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazole-5-carb...)
Affinity DataIC50:  1.60E+3nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142066((S)-2-[(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidaz...)
Affinity DataIC50:  1.90E+3nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142055((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50:  2.00E+3nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142067(CHEMBL176017 | [(1-Cyclohexyl-2-pyridin-2-yl-1H-be...)
Affinity DataIC50:  2.00E+3nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142068((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50:  2.20E+3nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142059((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50:  2.90E+3nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142058(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Affinity DataIC50:  3.00E+3nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142054((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50:  4.00E+3nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137468(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Affinity DataIC50:  7.00E+3nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142046((S)-2-[(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidaz...)
Affinity DataIC50:  7.00E+3nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142060(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Affinity DataIC50:  1.20E+4nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142052((2S)-2-(1-cyclohexyl-2-(furan-3-yl)-1H-benzo[d]imi...)
Affinity DataIC50:  7.90E+4nMAssay Description:Concentration required to inhibit RNA dependent RNA polymerase was determined from polio virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142043((2S)-3-(5-(carboxymethoxy)-1H-indol-3-yl)-2-(1-cyc...)
Affinity DataIC50:  1.00E+5nMAssay Description:Concentration required to inhibit DNA dependent RNA polymerase was determined from calf thymusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142045((S)-3-(5-Acetylamino-1H-indol-3-yl)-2-[(1-cyclohex...)
Affinity DataIC50: >1.25E+5nMAssay Description:Concentration required to inhibit RNA dependent RNA polymerase was determined from polio virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142056((S)-3-(5-Carbamoyl-1H-indol-3-yl)-2-[(1-cyclohexyl...)
Affinity DataIC50: >2.00E+5nMAssay Description:Concentration required to inhibit RNA dependent RNA polymerase was determined from polio virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142052((2S)-2-(1-cyclohexyl-2-(furan-3-yl)-1H-benzo[d]imi...)
Affinity DataIC50: >2.00E+5nMAssay Description:Concentration required to inhibit DNA dependent RNA polymerase was determined from calf thymusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142041(3-{(S)-2-Carboxy-2-[(1-cyclohexyl-2-furan-3-yl-1H-...)
Affinity DataIC50: >2.00E+5nMAssay Description:Concentration required to inhibit RNA dependent RNA polymerase was determined from polio virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142047((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50: >2.00E+5nMAssay Description:Concentration required to inhibit DNA dependent RNA polymerase was determined from calf thymusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142061((2S)-2-(1-cyclohexyl-2-(furan-3-yl)-1H-benzo[d]imi...)
Affinity DataIC50:  2.00E+5nMAssay Description:Concentration required to inhibit RNA dependent RNA polymerase was determined from polio virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142043((2S)-3-(5-(carboxymethoxy)-1H-indol-3-yl)-2-(1-cyc...)
Affinity DataIC50: >2.00E+5nMAssay Description:Concentration required to inhibit DNA dependent RNA polymerase was determined from calf thymusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142044((S)-3-[5-(1-Carboxy-1-methyl-ethoxy)-1H-indol-3-yl...)
Affinity DataIC50: >2.00E+5nMAssay Description:Concentration required to inhibit RNA dependent RNA polymerase was determined from polio virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142048((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50: >2.50E+5nMAssay Description:Concentration required to inhibit RNA dependent RNA polymerase was determined from polio virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142056((S)-3-(5-Carbamoyl-1H-indol-3-yl)-2-[(1-cyclohexyl...)
Affinity DataIC50: >2.50E+5nMAssay Description:Concentration required to inhibit RNA dependent RNA polymerase was determined from polio virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142041(3-{(S)-2-Carboxy-2-[(1-cyclohexyl-2-furan-3-yl-1H-...)
Affinity DataIC50: >2.50E+5nMAssay Description:Concentration required to inhibit DNA dependent RNA polymerase was determined from calf thymusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142045((S)-3-(5-Acetylamino-1H-indol-3-yl)-2-[(1-cyclohex...)
Affinity DataIC50: >2.50E+5nMAssay Description:Concentration required to inhibit DNA dependent RNA polymerase was determined from calf thymusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142048((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50: >2.50E+5nMAssay Description:Concentration required to inhibit RNA dependent RNA polymerase was determined from polio virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142042((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50: >2.50E+5nMAssay Description:Concentration required to inhibit DNA dependent RNA polymerase was determined from calf thymusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142053((S)-3-(5-Amino-1H-indol-3-yl)-2-[(1-cyclohexyl-2-f...)
Affinity DataIC50: >2.50E+5nMAssay Description:Concentration required to inhibit DNA dependent RNA polymerase was determined from calf thymusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142047((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50: >2.50E+5nMAssay Description:Concentration required to inhibit DNA dependent RNA polymerase was determined from calf thymusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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