Compile Data Set for Download or QSAR
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Found 20 Enz. Inhib. hit(s) with all data for entry = 50014539
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144204(CHEMBL63989 | [4-(2-Chloro-4,6-dimethoxy-phenyl)-p...)
Affinity DataKi:  11nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144193(CHEMBL65484 | Dicyclopropylmethyl-propyl-[4-(2,4,6...)
Affinity DataKi:  15nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144191(CHEMBL61954 | Dicyclopropylmethyl-[4-(2,4-dimethox...)
Affinity DataKi:  15nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144194(CHEMBL293627 | Dicyclopropylmethyl-[4-(2,4-dimetho...)
Affinity DataKi:  19nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144196(CHEMBL63029 | [4-(4-Bromo-phenyl)-5-methyl-pyrimid...)
Affinity DataKi:  49nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144200(CHEMBL63457 | Dicyclopropylmethyl-[4-(2-fluoro-4,6...)
Affinity DataKi:  63nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144197(CHEMBL66249 | [4-(4-Bromo-2-methyl-phenyl)-5-methy...)
Affinity DataKi:  63nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144203(Allyl-dicyclopropylmethyl-[4-(2,4,6-trimethoxy-phe...)
Affinity DataKi:  100nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144192(CHEMBL291657 | [4-(4-Bromo-phenyl)-5,6-dimethyl-py...)
Affinity DataKi:  240nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144202(((R)-Cyclopropyl-phenyl-methyl)-propyl-[4-(2,4,6-t...)
Affinity DataKi:  240nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144190(CHEMBL302396 | Propyl-(1-thiophen-2-yl-cyclopropyl...)
Affinity DataKi:  250nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144201(CHEMBL305354 | Dicyclopropylmethyl-[4-(2,4-dimetho...)
Affinity DataKi:  460nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144199((1-Furan-3-yl-cyclopropyl)-propyl-[4-(2,4,6-trimet...)
Affinity DataKi:  700nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144195(CHEMBL63585 | Dicyclopropylmethyl-[4-(2,4-dimethox...)
Affinity DataKi:  860nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144198(CHEMBL305583 | Propyl-(1-thiophen-3-yl-cyclopropyl...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144189(CHEMBL65979 | Cyclopentyl-propyl-[4-(2,4,6-trimeth...)
Affinity DataKi:  2.20E+3nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144204(CHEMBL63989 | [4-(2-Chloro-4,6-dimethoxy-phenyl)-p...)
Affinity DataEC50:  1.10E+3nMAssay Description:Effective dose of the compound against CRF stimulated cAMP production in CHO cells expressing human Corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144193(CHEMBL65484 | Dicyclopropylmethyl-propyl-[4-(2,4,6...)
Affinity DataEC50:  970nMAssay Description:Effective dose of the compound against CRF stimulated cAMP production in CHO cells expressing human Corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144193(CHEMBL65484 | Dicyclopropylmethyl-propyl-[4-(2,4,6...)
Affinity DataEC50:  990nMAssay Description:Effective dose of the compound against human Corticotropin releasing factor receptor 1 stimulated ACTH release from primary rat anterior pituitary ce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144204(CHEMBL63989 | [4-(2-Chloro-4,6-dimethoxy-phenyl)-p...)
Affinity DataEC50:  1.60E+3nMAssay Description:Effective dose of the compound against human Corticotropin releasing factor receptor 1 stimulated ACTH release from primary rat anterior pituitary ce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed