Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50014569
TargetHistamine H1 receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144624BDBM50144624((5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-pipera...)
Affinity DataKi:  4nMAssay Description:In vitro binding affinity towards histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 22890BDBM22890(CHEMBL1000 | 2-(2-{4-[(4-chlorophenyl)(phenyl)meth...)
Affinity DataKi:  14nMAssay Description:In vitro binding affinity towards histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144626BDBM50144626([4-((2S,5S)-5-{4-[(R)-(4-Chloro-phenyl)-phenyl-met...)
Affinity DataKi:  50nMAssay Description:In vitro binding affinity towards histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144621BDBM50144621(N-(4-{(2S,5S)-5-[(4-fluorophenoxy)methyl]tetrahydr...)
Affinity DataIC50: 117nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in a human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144623BDBM50144623([4-((2S,5S)-5-{4-[Bis-(4-fluoro-phenyl)-methyl]-pi...)
Affinity DataIC50: 140nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in a human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144625BDBM50144625(1-[4-(5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-p...)
Affinity DataKi:  150nMAssay Description:In vitro binding affinity towards histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029781BDBM50029781((R)-(+)-N-{3-[5-(4-fluorobenzyl)thien-2-yl]-1-meth...)
Affinity DataIC50: 160nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in a human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144620BDBM50144620([4-(5-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-...)
Affinity DataIC50: 170nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in a human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144627BDBM50144627([4-((2R,5R)-5-{4-[(R)-(4-Chloro-phenyl)-phenyl-met...)
Affinity DataKi:  180nMAssay Description:In vitro binding affinity towards histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144622BDBM50144622([3-(5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-pip...)
Affinity DataKi:  190nMAssay Description:In vitro binding affinity towards histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144625BDBM50144625(1-[4-(5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-p...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in an RBL-2H3 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144620BDBM50144620([4-(5-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in an RBL-2H3 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144626BDBM50144626([4-((2S,5S)-5-{4-[(R)-(4-Chloro-phenyl)-phenyl-met...)
Affinity DataIC50: 310nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in a human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144625BDBM50144625(1-[4-(5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-p...)
Affinity DataIC50: 420nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in a human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144627BDBM50144627([4-((2R,5R)-5-{4-[(R)-(4-Chloro-phenyl)-phenyl-met...)
Affinity DataIC50: 510nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in a human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144620BDBM50144620([4-(5-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-...)
Affinity DataKi:  550nMAssay Description:In vitro binding affinity towards histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144623BDBM50144623([4-((2S,5S)-5-{4-[Bis-(4-fluoro-phenyl)-methyl]-pi...)
Affinity DataKi:  660nMAssay Description:In vitro binding affinity towards histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000541BDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 873nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in a human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144624BDBM50144624((5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-pipera...)
Affinity DataIC50: 1.70E+3nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in a human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144622BDBM50144622([3-(5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-pip...)
Affinity DataIC50: 3.50E+3nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in a human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed