Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50014623
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145391BDBM50145391((1S,3R,8AS)-8-(2-{(4S,6S)-3-(4-HYDROXY-3-METHOXYBE...)
Affinity DataIC50: 50nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145392BDBM50145392((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)
Affinity DataIC50: 50nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145392BDBM50145392((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)
Affinity DataIC50: 120nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145394BDBM50145394((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)
Affinity DataIC50: 170nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145391BDBM50145391((1S,3R,8AS)-8-(2-{(4S,6S)-3-(4-HYDROXY-3-METHOXYBE...)
Affinity DataIC50: 250nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145395BDBM50145395((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)
Affinity DataIC50: 270nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145396BDBM50145396((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-3,7-di...)
Affinity DataIC50: 620nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145390BDBM50145390((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)
Affinity DataIC50: 640nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145388BDBM50145388((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)
Affinity DataIC50: 680nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145398BDBM50145398((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)
Affinity DataIC50: 800nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145385BDBM50145385(4-((1R,5R)-6-{2-[(1S,2S,6R,8S,8aR)-2,6-Dimethyl-8-...)
Affinity DataIC50: 870nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145397BDBM50145397((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145386BDBM50145386((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)
Affinity DataIC50: 1.15E+3nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145393BDBM50145393((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)
Affinity DataIC50: 1.30E+3nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145399BDBM50145399((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145397BDBM50145397((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)
Affinity DataIC50: 2.59E+3nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145387BDBM50145387((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004774BDBM50004774(2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrah...)
Affinity DataIC50: 3.78E+3nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145388BDBM50145388((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145386BDBM50145386((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)
Affinity DataIC50: 5.59E+3nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145394BDBM50145394((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)
Affinity DataIC50: 6.42E+3nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145395BDBM50145395((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145387BDBM50145387((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)
Affinity DataIC50: 7.69E+3nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145398BDBM50145398((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145390BDBM50145390((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145389BDBM50145389((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145385BDBM50145385(4-((1R,5R)-6-{2-[(1S,2S,6R,8S,8aR)-2,6-Dimethyl-8-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145389BDBM50145389((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145393BDBM50145393((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145396BDBM50145396((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-3,7-di...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed