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Found 17 Enz. Inhib. hit(s) with all data for entry = 50037317
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146629(CHEMBL330040 | N-Hydroxy-2-[(4-nitro-benzyl)-(4-tr...)
Affinity DataKi:  3nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50088118(2-(N-(4-nitrobenzyl)-2,3,4,5,6-pentafluorophenylsu...)
Affinity DataKi:  5nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082556((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...)
Affinity DataKi:  8.20nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataKi:  33nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146636(2-{4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYL]-TETRAH...)
Affinity DataKi:  70nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146633(1-[4-(4-Imidazol-1-yl-phenoxy)-piperidine-1-sulfon...)
Affinity DataKi:  224nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146635(1-(4-Pyridin-2-yl-piperazine-1-sulfonyl)-piperidin...)
Affinity DataKi:  423nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146634(CHEMBL328903 | N*1*-(2,2-Dimethyl-1-methylcarbamoy...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146639(1-[4-(2,4-Dimethyl-benzyloxy)-benzenesulfonyl]-3-h...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071839(4-Benzoyl-1-(4-phenoxy-benzenesulfonyl)-[1,4]diaze...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146631((S)-2-[(S)-2-((R)-2-Hydroxycarbamoylmethyl-4-methy...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146638(3-[[4-(4-Fluoro-phenoxy)-benzenesulfonyl]-(1-hydro...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146628(2-(4-But-2-ynyloxy-benzenesulfonyl)-1,2,3,4-tetrah...)
Affinity DataIC50:  121nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146632(2-[(4-Buta-2,3-dienyloxy-benzenesulfonyl)-methyl-a...)
Affinity DataIC50:  138nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146640(2-[4-(5-Chloro-pyridin-2-yloxy)-piperidine-1-sulfo...)
Affinity DataIC50:  360nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146637(1-(4-Butoxy-benzenesulfonyl)-4-morpholin-4-yl-pyrr...)
Affinity DataIC50:  920nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed