Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50022540
LigandPNGBDBM50652891(CHEMBL5665391)
Affinity DataIC50: 2nMAssay Description:Inhibition of HER2 in human BT-474 cells assessed as reduction in MAPK phosphorylation incubated for 12 to 16 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652891(CHEMBL5665391)
Affinity DataIC50: 2nMAssay Description:Inhibition of HER2 in human BT-474 cells assessed as reduction in AKT phosphorylation incubated for 12 to 16 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652891(CHEMBL5665391)
Affinity DataIC50: 3nMAssay Description:Inhibition of EGF-induced EGFR phosphorylation in human A-431 cells incubated for 3 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652891(CHEMBL5665391)
Affinity DataIC50: 5nMAssay Description:Inhibition of HER2 autophosphorylation in human BT-474 cells measured after 3 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-etho...)
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant N-terminal His6-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652891(CHEMBL5665391)
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant N-terminal His6-tagged HER2 cytoplasmic domain (676 to 1255 residues) (unknown origin) expressed in baculovirus infected Sf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652891(CHEMBL5665391)
Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant N-terminal His6-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652891(CHEMBL5665391)
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant KDR (unknown origin) using poly[Glu:Tyr] (4:1) as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-etho...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of recombinant N-terminal His6-tagged HER2 cytoplasmic domain (676 to 1255 residues) (unknown origin) expressed in baculovirus infected Sf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652891(CHEMBL5665391)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant Src (unknown origin) using peptide as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652891(CHEMBL5665391)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant PDK1 (unknown origin) using peptide as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652891(CHEMBL5665391)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of recombinant IKK-2 (unknown origin) using peptide as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652891(CHEMBL5665391)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of recombinant CDK1/cyclin B1 (unknown origin) using protein as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652891(CHEMBL5665391)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of recombinant c-Raf (unknown origin) using protein as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652891(CHEMBL5665391)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of recombinant Tpl-2 (unknown origin) using peptide as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652891(CHEMBL5665391)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of recombinant CDK2/cyclin E (unknown origin) using protein as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652891(CHEMBL5665391)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant AKT (unknown origin) using peptide as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652891(CHEMBL5665391)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of recombinant c-Met autophosphorylation (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652891(CHEMBL5665391)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of recombinant MK2 (unknown origin) using peptide as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652891(CHEMBL5665391)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant CDK4/cyclin D1 (unknown origin) using protein as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed