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Found 36 Enz. Inhib. hit(s) with all data for entry = 50014938
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50092485(4-methyl-8-chloro-1,2,5,6-tetrahydro pyrido[1,2-a]...)
Affinity DataIC50:  5.80nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149341(8-Bromo-4-methyl-1,2,5,6-tetrahydro-pyrido[1,2-a]q...)
Affinity DataIC50:  8.10nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149339(4-Methyl-8-phenylethynyl-1,2,5,6-tetrahydro-pyrido...)
Affinity DataIC50:  8.75nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149329(8-Ethyl-4-methyl-1,2,5,6-tetrahydro-pyrido[1,2-a]q...)
Affinity DataIC50:  14nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149324(4-Methyl-8-((Z)-styryl)-1,2,5,6-tetrahydro-pyrido[...)
Affinity DataIC50:  14.2nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50092492(4,8-Dimethyl-1,2,5,6-tetrahydro-pyrido[1,2-a]quino...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50025356(4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10...)
Affinity DataIC50:  21nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type 2 in stably transfected chinese hamster ovary 1827 cells using [3H]...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149335(4-Methyl-8-vinyl-1,2,5,6-tetrahydro-pyrido[1,2-a]q...)
Affinity DataIC50:  21.6nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50085564(8-Chloro-1,2,5,6-tetrahydro-pyrido[1,2-a]quinolin-...)
Affinity DataIC50:  49nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149326(4-Methyl-8-thiophen-2-yl-1,2,5,6-tetrahydro-pyrido...)
Affinity DataIC50:  79nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149325(4-Methyl-8-(4-trifluoromethyl-benzyloxy)-1,2,5,6-t...)
Affinity DataIC50:  83.7nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149332(8-(4-Chloro-benzyloxy)-4-methyl-1,2,5,6-tetrahydro...)
Affinity DataIC50:  92.9nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149340(8-(3-Chloro-benzyloxy)-4-methyl-1,2,5,6-tetrahydro...)
Affinity DataIC50:  93nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149343(4-Methyl-3-oxo-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]...)
Affinity DataIC50:  96.8nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149321(8-Benzyloxy-4-methyl-1,2,5,6-tetrahydro-pyrido[1,2...)
Affinity DataIC50:  111nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149345(4-Methyl-3-oxo-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]...)
Affinity DataIC50:  117nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149330(4-Methyl-3-oxo-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]...)
Affinity DataIC50:  121nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149344(4-Methyl-8-phenyl-1,2,5,6-tetrahydro-pyrido[1,2-a]...)
Affinity DataIC50:  128nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149333(8-Furan-2-yl-4-methyl-1,2,5,6-tetrahydro-pyrido[1,...)
Affinity DataIC50:  133nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149319(8-(2,4-Bis-trifluoromethyl-benzyloxy)-4-methyl-1,2...)
Affinity DataIC50:  149nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149322(4-Methyl-8-pyridin-3-yl-1,2,5,6-tetrahydro-pyrido[...)
Affinity DataIC50:  170nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149338(8-Methoxy-4-methyl-1,2,5,6-tetrahydro-pyrido[1,2-a...)
Affinity DataIC50:  178nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50092502(4-Methyl-1,2,5,6-tetrahydro-pyrido[1,2-a]quinolin-...)
Affinity DataIC50:  185nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149334(8-(2-Chloro-benzyloxy)-4-methyl-1,2,5,6-tetrahydro...)
Affinity DataIC50:  194nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149342(4-Methyl-3-oxo-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]...)
Affinity DataIC50:  221nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50072191(1,2,5,6-Tetrahydro-pyrido[1,2-a]quinolin-3-one | 1...)
Affinity DataIC50:  298nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50092497(8-Methyl-1,2,5,6-tetrahydro-pyrido[1,2-a]quinolin-...)
Affinity DataIC50:  376nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149327(4-Methyl-8-((E)-styryl)-1,2,5,6-tetrahydro-pyrido[...)
Affinity DataIC50:  380nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149328(8-(2,5-Bis-trifluoromethyl-benzyloxy)-4-methyl-1,2...)
Affinity DataIC50:  393nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149337(4-Methyl-3-oxo-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]...)
Affinity DataIC50:  560nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149336(4-Methyl-3-oxo-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]...)
Affinity DataIC50:  731nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50025356(4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10...)
Affinity DataIC50:  911nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149331(4-Methyl-3-oxo-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]...)
Affinity DataIC50:  942nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149323(4-Methyl-3-oxo-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]...)
Affinity DataIC50:  965nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149320(4-Methyl-3-oxo-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50149346(4-Methyl-3-oxo-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]...)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed