Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50014968
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149693BDBM50149693(2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-2-oxo-N-(2-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149695BDBM50149695(2-(4-Benzyl-piperidin-1-yl)-2-oxo-N-(2-oxo-2,3-dih...)
Affinity DataIC50: 3nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149684BDBM50149684(2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-2-oxo-N-(2-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50079385BDBM50079385(1-[2-(4-Hydroxy-phenoxy)-ethyl]-4-(4-methyl-benzyl...)
Affinity DataIC50: 5nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149687BDBM50149687(2-[4-(4-Chloro-phenoxy)-piperidin-1-yl]-2-oxo-N-(2...)
Affinity DataIC50: 6nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149689BDBM50149689(2-(4-Benzyl-piperidin-1-yl)-2-oxo-N-(2-oxo-2,3-dih...)
Affinity DataIC50: 6nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149685BDBM50149685(2-[4-(4-Chloro-phenoxy)-piperidin-1-yl]-2-oxo-N-(2...)
Affinity DataIC50: 7nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149691BDBM50149691(2-Oxo-N-(2-oxo-2,3-dihydro-benzothiazol-6-yl)-2-(4...)
Affinity DataIC50: 8nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204884BDBM50204884(6-(2-(4-(4-fluorobenzyl)piperidin-1-yl)ethylsulfin...)
Affinity DataIC50: 8nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149692BDBM50149692(2-(4-Benzyl-piperidin-1-yl)-2-oxo-N-(2-oxo-2,3-dih...)
Affinity DataIC50: 9nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149697BDBM50149697(2-Oxo-N-(2-thioxo-2,3-dihydro-1H-benzoimidazol-5-y...)
Affinity DataIC50: 10nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149694BDBM50149694(2-[4-(4-Methyl-benzyl)-piperidin-1-yl]-2-oxo-N-(2-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149696BDBM50149696(2-[4-(4-Methyl-benzyl)-piperidin-1-yl]-2-oxo-N-(3-...)
Affinity DataIC50: 18nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149688BDBM50149688(2-(4-Benzyl-piperidin-1-yl)-2-oxo-N-(2-oxo-1,4-dih...)
Affinity DataIC50: 29nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50032651BDBM50032651(1-[(1S,2S)-2-Hydroxy-2-(4-hydroxy-phenyl)-1-methyl...)
Affinity DataIC50: 30nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149690BDBM50149690(2-(4-Benzyl-piperidin-1-yl)-N-(4-hydroxy-phenyl)-2...)
Affinity DataIC50: 31nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134657BDBM50134657((4-Benzyl-piperidin-1-yl)-(5-hydroxy-1H-indol-2-yl...)
Affinity DataIC50: 42nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149686BDBM50149686(6-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propiony...)
Affinity DataIC50: 48nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080029BDBM50080029(CHEMBL305195 | 4-[(1R,2S)-3-(4-Benzyl-piperidin-1-...)
Affinity DataIC50: 57nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed