Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50014977
LigandChemical structure of BindingDB Monomer ID 50149846BDBM50149846(2''-Amino-6''-(2-cyclopropylmethoxy-6-hydroxy-phen...)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149839BDBM50149839(2''-Amino-6''-(2-cyclobutylmethoxy-6-hydroxy-pheny...)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149833BDBM50149833(2''-Amino-6''-(2-hydroxy-6-isobutoxy-phenyl)-1,2,3...)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149832BDBM50149832(2''-Amino-6''-(2-hydroxy-6-propoxy-phenyl)-1,2,3,4...)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149838BDBM50149838(2''-Amino-6''-(2-hydroxy-6-pentyloxy-phenyl)-1,2,3...)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149825BDBM50149825(2-Amino-6-(2-cyclopropylmethoxy-6-hydroxy-phenyl)-...)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149843BDBM50149843(2''-Amino-6''-(2-benzyloxy-6-hydroxy-phenyl)-1,2,3...)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149828BDBM50149828(2-Amino-6-(2-cyclobutylmethoxy-6-hydroxy-phenyl)-1...)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149831BDBM50149831(2''-Amino-6''-(2-heptyloxy-6-hydroxy-phenyl)-1,2,3...)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149852BDBM50149852(2''-Amino-6''-(2-ethoxy-6-hydroxy-phenyl)-1,2,3,4,...)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149850BDBM50149850(2-Amino-6-(2-butoxy-6-hydroxy-phenyl)-1'',2'',3'',...)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149842BDBM50149842(2''-Amino-6''-(2,6-dihydroxy-phenyl)-1,2,3,4,5,6-h...)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149837BDBM50149837(2-Amino-6-(2-hydroxy-6-isobutoxy-phenyl)-1'',2'',3...)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149826BDBM50149826(2-Amino-6-(2-hydroxy-6-pentyloxy-phenyl)-1'',2'',3...)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149840BDBM50149840(2-Amino-6-(2-hydroxy-6-propoxy-phenyl)-1'',2'',3''...)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149806BDBM50149806(2''-Amino-6''-(2-hydroxy-phenyl)-1,2,3,4,5,6-hexah...)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149834BDBM50149834(2-Amino-6-(2-hexyloxy-6-hydroxy-phenyl)-1'',2'',3'...)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149835BDBM50149835(2''-Amino-6''-(2-cyclohexylmethoxy-6-hydroxy-pheny...)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149836BDBM50149836(2''-Amino-6''-(2-hydroxy-6-methoxy-phenyl)-1,2,3,4...)
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149830BDBM50149830(2-Amino-6-(2-heptyloxy-6-hydroxy-phenyl)-1'',2'',3...)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149815BDBM50149815(2-Amino-4-(1-amino-2-phenyl-ethyl)-6-(2-hydroxy-ph...)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149851BDBM50149851(2''-Amino-6''-(2-hydroxy-6-isopropoxy-phenyl)-1,2,...)
Affinity DataIC50: 81nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149848BDBM50149848(2-Amino-6-(2-benzyloxy-6-hydroxy-phenyl)-1'',2'',3...)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149841BDBM50149841(2-Amino-6-(2-ethoxy-6-hydroxy-phenyl)-1'',2'',3'',...)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149825BDBM50149825(2-Amino-6-(2-cyclopropylmethoxy-6-hydroxy-phenyl)-...)
Affinity DataIC50: 250nMAssay Description:Inhibition of I-kappa-B-kinase alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149829BDBM50149829(2-Amino-6-(2,6-dihydroxy-phenyl)-1'',2'',3'',4'',5...)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149810BDBM50149810(2-Amino-6-(2-hydroxy-phenyl)-1'',2'',3'',4'',5'',6...)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149847BDBM50149847(2''-Amino-6''-(2-hydroxy-4-methoxy-phenyl)-1,2,3,4...)
Affinity DataIC50: 560nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149827BDBM50149827(2''-Amino-6''-(2-hydroxy-3-methyl-phenyl)-1,2,3,4,...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50124313BDBM50124313(5-Oxo-tetrahydro-furan-2-carboxylic acid {3-[2-ami...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149844BDBM50149844(2''-Amino-6''-(2-hydroxy-6-methyl-phenyl)-1,2,3,4,...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149849BDBM50149849(2''-Amino-6''-(2-amino-6-hydroxy-phenyl)-1,2,3,4,5...)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kyoto 619-0216

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149825BDBM50149825(2-Amino-6-(2-cyclopropylmethoxy-6-hydroxy-phenyl)-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Syk protein tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149825BDBM50149825(2-Amino-6-(2-cyclopropylmethoxy-6-hydroxy-phenyl)-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of I-kappa-B-kinase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149845BDBM50149845(2''-Amino-6''-(2-hydroxy-3-methoxy-phenyl)-1,2,3,4...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed