Compile Data Set for Download or QSAR
maximum 50k data
Found 20 Enz. Inhib. hit(s) with all data for entry = 3311
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM31225(2-phenoxybenzoyltryptophan derivative, R5C3)
Affinity DataKi:  100nM ΔG°:  -39.7kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM31224(2-phenoxybenzoyltryptophan derivative, R5C2)
Affinity DataKi:  200nM ΔG°:  -38.0kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM31216(2-phenoxybenzoyltryptophan derivative, R3C2)
Affinity DataKi:  400nM ΔG°:  -36.3kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM31209(2-phenoxybenzoyltryptophan derivative, R1C3)
Affinity DataKi:  500nM ΔG°:  -35.7kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM31226(2-phenoxybenzoyltryptophan derivative, R5C4)
Affinity DataKi:  600nM ΔG°:  -35.3kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM31210(2-phenoxybenzoyltryptophan derivative, R1C4)
Affinity DataKi:  600nM ΔG°:  -35.3kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM31213(2-phenoxybenzoyltryptophan derivative, R2C3)
Affinity DataKi:  600nM ΔG°:  -35.3kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM31220(2-phenoxybenzoyltryptophan derivative, R4C2)
Affinity DataKi:  600nM ΔG°:  -35.3kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM31221(2-phenoxybenzoyltryptophan derivative, R4C3)
Affinity DataKi:  600nM ΔG°:  -35.3kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM31217(2-phenoxybenzoyltryptophan derivative, R3C3)
Affinity DataKi:  800nM ΔG°:  -34.6kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM31212(2-phenoxybenzoyltryptophan derivative, R2C2)
Affinity DataKi:  800nM ΔG°:  -34.6kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM31208(2-phenoxybenzoyltryptophan derivative, R1C2)
Affinity DataKi:  800nM ΔG°:  -34.6kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM31222(2-phenoxybenzoyltryptophan derivative, R4C4)
Affinity DataKi:  1.00E+3nM ΔG°:  -34.0kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM31214(2-phenoxybenzoyltryptophan derivative, R2C4)
Affinity DataKi:  1.00E+3nM ΔG°:  -34.0kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM31218(2-phenoxybenzoyltryptophan derivative, R3C4)
Affinity DataKi:  2.00E+3nM ΔG°:  -32.3kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM31207(2-phenoxybenzoyltryptophan derivative, R1C1)
Affinity DataKi:  3.00E+3nM ΔG°:  -31.3kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM31211(2-phenoxybenzoyltryptophan derivative, R2C1)
Affinity DataKi:  6.00E+3nM ΔG°:  -29.6kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM31223(2-phenoxybenzoyltryptophan derivative, R5C1)
Affinity DataKi:  1.00E+4nM ΔG°:  -28.3kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM31219(2-phenoxybenzoyltryptophan derivative, R4C1)
Affinity DataKi:  1.00E+4nM ΔG°:  -28.3kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM31215(2-phenoxybenzoyltryptophan derivative, R3C1)
Affinity DataKi:  2.00E+4nM ΔG°:  -26.6kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed