Compile Data Set for Download or QSAR
maximum 50k data
Found 35 Enz. Inhib. hit(s) with all data for entry = 1987
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM12372(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  3nM ΔG°:  -48.6kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15848(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  12nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15843(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  14nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15824(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  18nM ΔG°:  -44.2kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15846(2-carboxyindole-based inhibitor 31 | N-{1-[(1-{[5-...)
Affinity DataKi:  18nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15828(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  27nM ΔG°:  -43.2kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15823(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  40nM ΔG°:  -42.2kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15839(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  48nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15845(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  64nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15825(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  64nM ΔG°:  -41.1kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15829(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  71nM ΔG°:  -40.8kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15844(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  95nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15834(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  95nM ΔG°:  -40.1kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15838(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  103nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15830(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  106nM ΔG°:  -39.8kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15836(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  125nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15833(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  131nM ΔG°:  -39.3kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15827(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  142nM ΔG°:  -39.1kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15832(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  161nM ΔG°:  -38.8kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15826(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  220nM ΔG°:  -38.0kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15840(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  225nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15841(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  345nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15835(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  763nM ΔG°:  -34.9kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15842(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  839nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15837(2-carboxyindole-based inhibitor 22 | N-(1-carbamoy...)
Affinity DataKi:  1.08E+3nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM12372(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  2.76E+3nM ΔG°:  -31.7kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human thrombin was determined by using the chromogenic substrates S-2366. The hydrolysis rates of chromoge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15847(2-carboxyindole-based inhibitor 32 | 5-(5-chloroth...)
Affinity DataKi:  2.90E+3nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15831(1-[(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]...)
Affinity DataKi:  3.00E+3nM ΔG°:  -31.5kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15846(2-carboxyindole-based inhibitor 31 | N-{1-[(1-{[5-...)
Affinity DataKi:  3.16E+3nMAssay Description:The inhibitory effect of test compound for human thrombin was determined by using the chromogenic substrates S-2366. The hydrolysis rates of chromoge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15828(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  8.22E+3nM ΔG°:  -29.0kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human thrombin was determined by using the chromogenic substrates S-2366. The hydrolysis rates of chromoge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15824(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human thrombin was determined by using the chromogenic substrates S-2366. The hydrolysis rates of chromoge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15823(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human thrombin was determined by using the chromogenic substrates S-2366. The hydrolysis rates of chromoge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15839(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi: >1.00E+4nMAssay Description:The inhibitory effect of test compound for human thrombin was determined by using the chromogenic substrates S-2366. The hydrolysis rates of chromoge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15843(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi: >1.00E+4nMAssay Description:The inhibitory effect of test compound for human thrombin was determined by using the chromogenic substrates S-2366. The hydrolysis rates of chromoge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM15848(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi: >1.00E+4nMAssay Description:The inhibitory effect of test compound for human thrombin was determined by using the chromogenic substrates S-2366. The hydrolysis rates of chromoge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed