Compile Data Set for Download or QSAR
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Found 36 Enz. Inhib. hit(s) with all data for entry = 50015265
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153608(4-[4-Hydroxy-4-(3-trifluoromethyl-phenyl)-piperidi...)
Affinity DataKi:  0.110nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50017686(4-[4-(4-Chloro-3-trifluoromethyl-phenyl)-4-hydroxy...)
Affinity DataKi:  0.110nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153614(4-[4-Hydroxy-4-(3-trifluoromethyl-phenyl)-piperidi...)
Affinity DataKi:  0.160nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153611(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2...)
Affinity DataKi:  0.230nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153613(4-[4-(4-Chloro-3-trifluoromethyl-phenyl)-4-hydroxy...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50017698(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N...)
Affinity DataKi:  0.530nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50132647(1-(3,3-Diphenyl-propyl)-4-(3-trifluoromethyl-pheny...)
Affinity DataKi:  1nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50132662(4-(4-Chloro-3-trifluoromethyl-phenyl)-1-naphthalen...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50132644(4-(4-Chloro-3-trifluoromethyl-phenyl)-1-(3,3-diphe...)
Affinity DataKi:  4nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153615(4-(4-Chloro-phenyl)-1-(3,3-diphenyl-propyl)-piperi...)
Affinity DataKi:  37nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153608(4-[4-Hydroxy-4-(3-trifluoromethyl-phenyl)-piperidi...)
Affinity DataKi:  78nMAssay Description:Binding affinity for opioid receptor like 1 expressed in HEK-293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50132651(4-(4-Chloro-3-trifluoromethyl-phenyl)-1-(4-trifluo...)
Affinity DataKi:  104nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50132647(1-(3,3-Diphenyl-propyl)-4-(3-trifluoromethyl-pheny...)
Affinity DataKi:  116nMAssay Description:Binding affinity for opioid receptor like 1 expressed in HEK-293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153613(4-[4-(4-Chloro-3-trifluoromethyl-phenyl)-4-hydroxy...)
Affinity DataKi:  149nMAssay Description:Binding affinity for opioid receptor like 1 expressed in HEK-293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50132644(4-(4-Chloro-3-trifluoromethyl-phenyl)-1-(3,3-diphe...)
Affinity DataKi:  225nMAssay Description:Binding affinity for opioid receptor like 1 expressed in HEK-293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153610(4-[4-Hydroxy-4-(3-trifluoromethyl-phenyl)-piperidi...)
Affinity DataKi:  331nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153615(4-(4-Chloro-phenyl)-1-(3,3-diphenyl-propyl)-piperi...)
Affinity DataKi:  372nMAssay Description:Binding affinity for opioid receptor like 1 expressed in HEK-293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153616(4-[4-(4-Chloro-3-trifluoromethyl-phenyl)-4-hydroxy...)
Affinity DataKi:  489nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153614(4-[4-Hydroxy-4-(3-trifluoromethyl-phenyl)-piperidi...)
Affinity DataKi:  505nMAssay Description:Binding affinity for opioid receptor like 1 expressed in HEK-293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153611(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2...)
Affinity DataKi:  590nMAssay Description:Binding affinity for opioid receptor like 1 expressed in HEK-293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50132662(4-(4-Chloro-3-trifluoromethyl-phenyl)-1-naphthalen...)
Affinity DataKi:  879nMAssay Description:Binding affinity for opioid receptor like 1 expressed in HEK-293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50132651(4-(4-Chloro-3-trifluoromethyl-phenyl)-1-(4-trifluo...)
Affinity DataKi:  1.19E+3nMAssay Description:Binding affinity for opioid receptor like 1 expressed in HEK-293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153617(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2...)
Affinity DataKi:  1.46E+3nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50017686(4-[4-(4-Chloro-3-trifluoromethyl-phenyl)-4-hydroxy...)
Affinity DataKi:  2.15E+3nMAssay Description:Binding affinity for opioid receptor like 1 expressed in HEK-293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153618(1-(3,3-Diphenyl-propyl)-1-oxy-4-(3-trifluoromethyl...)
Affinity DataKi:  8.13E+3nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153617(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for opioid receptor like 1 expressed in HEK-293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153612(4-(4-Chloro-3-trifluoromethyl-phenyl)-1-naphthalen...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for opioid receptor like 1 expressed in HEK-293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153618(1-(3,3-Diphenyl-propyl)-1-oxy-4-(3-trifluoromethyl...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for opioid receptor like 1 expressed in HEK-293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153609(4-(4-Chloro-3-trifluoromethyl-phenyl)-1-(3,3-diphe...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for opioid receptor like 1 expressed in HEK-293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153616(4-[4-(4-Chloro-3-trifluoromethyl-phenyl)-4-hydroxy...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for opioid receptor like 1 expressed in HEK-293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50132653(4-[4-(4-Chloro-3-trifluoromethyl-phenyl)-4-hydroxy...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153610(4-[4-Hydroxy-4-(3-trifluoromethyl-phenyl)-piperidi...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for opioid receptor like 1 expressed in HEK-293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50132653(4-[4-(4-Chloro-3-trifluoromethyl-phenyl)-4-hydroxy...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for opioid receptor like 1 expressed in HEK-293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153612(4-(4-Chloro-3-trifluoromethyl-phenyl)-1-naphthalen...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153609(4-(4-Chloro-3-trifluoromethyl-phenyl)-1-(3,3-diphe...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50017698(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for opioid receptor like 1 expressed in HEK-293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed