Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 50015280
LigandPNGBDBM50126335(6-[(R)-Amino-(4-chloro-phenyl)-(3-methyl-3H-imidaz...)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of Bovine farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

LigandPNGBDBM50153770(1-(3-Chloro-phenyl)-6-({[3-(4-cyano-benzyl)-3H-imi...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of Bovine farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14459((+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H...)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of Bovine farnesyltransferase (FTase)More data for this Ligand-Target Pair
LigandPNGBDBM50153768(1-(3-Chloro-phenyl)-6-[(4-cyano-phenyl)-(3-methyl-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of Bovine farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50153771(1-(3-Chloro-phenyl)-7-[(4-chloro-phenyl)-hydroxy-(...)
Affinity DataIC50:  12nMAssay Description:Inhibition of Bovine farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50153769(5-(3-Chloro-phenyl)-6-({[3-(4-cyano-benzyl)-3H-imi...)
Affinity DataIC50:  17nMAssay Description:Inhibition of Bovine farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50153772(CHEMBL184113 | N-[1-(3-Chloro-phenyl)-5-cyano-4-ox...)
Affinity DataIC50:  160nMAssay Description:Inhibition of Bovine farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50153773(4-(3-Chloro-phenyl)-1-methyl-6-oxo-1,6-dihydro-pyr...)
Affinity DataIC50:  685nMAssay Description:Inhibition of Bovine farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50126335(6-[(R)-Amino-(4-chloro-phenyl)-(3-methyl-3H-imidaz...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Bovine geranylgeranyltransferase (GGT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

LigandPNGBDBM50153769(5-(3-Chloro-phenyl)-6-({[3-(4-cyano-benzyl)-3H-imi...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Bovine geranylgeranyltransferase (GGT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50153768(1-(3-Chloro-phenyl)-6-[(4-cyano-phenyl)-(3-methyl-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Bovine geranylgeranyltransferase (GGT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14459((+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Bovine geranylgeranyltransferase (GGT)More data for this Ligand-Target Pair
LigandPNGBDBM50153770(1-(3-Chloro-phenyl)-6-({[3-(4-cyano-benzyl)-3H-imi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Bovine geranylgeranyltransferase (GGT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50153771(1-(3-Chloro-phenyl)-7-[(4-chloro-phenyl)-hydroxy-(...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of Bovine geranylgeranyltransferase (GGT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50153769(5-(3-Chloro-phenyl)-6-({[3-(4-cyano-benzyl)-3H-imi...)
Affinity DataEC50:  21nMAssay Description:Inhibition of Ras farnesylation in H-Ras transformed NIH3T3 cells at 100 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50126335(6-[(R)-Amino-(4-chloro-phenyl)-(3-methyl-3H-imidaz...)
Affinity DataEC50:  1.60nMAssay Description:Inhibition of Ras farnesylation in H-Ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14459((+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H...)
Affinity DataEC50:  100nMAssay Description:Inhibition of Ras farnesylation in H-Ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair