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Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50037463
TargetAldo-keto reductase family 1 member B1(Pig)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of aldose reductase from pig lensesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)

TargetAldo-keto reductase family 1 member B1(Pig)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of aldose reductase from pig lensesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetAldo-keto reductase family 1 member B1(Pig)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50154219(1-(4-Chloro-benzyl)-5-oxo-pyrrolidine-3-carboxylic...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of aldose reductase from pig lensesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAldo-keto reductase family 1 member B1(Pig)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50154216(CHEMBL186124 | [1-(3-Chloro-benzyl)-1H-indol-3-yl]...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of aldose reductase from pig lensesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAldo-keto reductase family 1 member B1(Pig)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50154218(1-(3-Bromo-phenyl)-5-phenyl-1H-[1,2,3]triazole-4-c...)
Affinity DataIC50:  2.74E+5nMAssay Description:Inhibition of aldose reductase from pig lensesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAldo-keto reductase family 1 member B1(Pig)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50154220(3-Benzyloxy-2-benzyloxycarbonylamino-butyric acid ...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of aldose reductase from pig lenses; no inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAldo-keto reductase family 1 member B1(Pig)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50154215(Bis-(4-chloro-benzyl)-(1H-tetrazol-5-yl)-amine | C...)
Affinity DataIC50:  3.36E+5nMAssay Description:Inhibition of aldose reductase from pig lensesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAldo-keto reductase family 1 member B1(Pig)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50154217(3-(4-Chloro-benzyloxy)-2-(3,3-dimethyl-butyrylamin...)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of aldose reductase from pig lenses; no inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed