Compile Data Set for Download or QSAR
maximum 50k data
Found 53 Enz. Inhib. hit(s) with all data for entry = 892
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6939(4-hydroxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-ind...)
Affinity DataIC50:  5nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6922(3,4-dihydroxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H...)
Affinity DataIC50:  5nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6914(N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]...)
Affinity DataIC50:  6.5nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6934(N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]...)
Affinity DataIC50:  7nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6941(3-amino-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-inden...)
Affinity DataIC50:  7nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6918(3,4,5-trimethoxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H...)
Affinity DataIC50:  7nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6920(3-amino-4-hydroxy-N-({[3-(4-methoxyphenyl)-4-oxo-2...)
Affinity DataIC50:  7nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6919(N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]...)
Affinity DataIC50:  7nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6927(acylsemicarbazide deriv. 3o | methoxy-N-({[3-(4-me...)
Affinity DataIC50:  8nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6939(4-hydroxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-ind...)
Affinity DataIC50:  9nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6936(N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]...)
Affinity DataIC50:  9nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6915(3-(4-hydroxyphenyl)-N-({[3-(4-methoxyphenyl)-4-oxo...)
Affinity DataIC50:  9nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6930(2-hydroxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-ind...)
Affinity DataIC50:  9nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6935(N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]...)
Affinity DataIC50:  9nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6917(N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]...)
Affinity DataIC50:  10nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6922(3,4-dihydroxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H...)
Affinity DataIC50:  10nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6942(4-amino-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-inden...)
Affinity DataIC50:  10nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6942(4-amino-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-inden...)
Affinity DataIC50:  10nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6916(4-methoxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-ind...)
Affinity DataIC50:  11nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6935(N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]...)
Affinity DataIC50:  12nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6934(N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]...)
Affinity DataIC50:  12nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6937(2,4-dihydroxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H...)
Affinity DataIC50:  12nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6919(N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]...)
Affinity DataIC50:  13nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6915(3-(4-hydroxyphenyl)-N-({[3-(4-methoxyphenyl)-4-oxo...)
Affinity DataIC50:  13nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6931(N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]...)
Affinity DataIC50:  13nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6941(3-amino-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-inden...)
Affinity DataIC50:  13nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6928(2-methoxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-ind...)
Affinity DataIC50:  14nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6916(4-methoxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-ind...)
Affinity DataIC50:  15nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6937(2,4-dihydroxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H...)
Affinity DataIC50:  16nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6936(N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]...)
Affinity DataIC50:  16nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6923(3,5-diamino-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-i...)
Affinity DataIC50:  16nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6927(acylsemicarbazide deriv. 3o | methoxy-N-({[3-(4-me...)
Affinity DataIC50:  16nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6925(3-[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]py...)
Affinity DataIC50:  19nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6914(N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]...)
Affinity DataIC50:  19nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6918(3,4,5-trimethoxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H...)
Affinity DataIC50:  20nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6917(N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]...)
Affinity DataIC50:  24nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6933(3,5-dimethoxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H...)
Affinity DataIC50:  24nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6929(N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]...)
Affinity DataIC50:  24nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6920(3-amino-4-hydroxy-N-({[3-(4-methoxyphenyl)-4-oxo-2...)
Affinity DataIC50:  24nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6932(N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]...)
Affinity DataIC50:  27nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6921(2,5-dichloro-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-...)
Affinity DataIC50:  28nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6932(N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]...)
Affinity DataIC50:  33nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6931(N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]...)
Affinity DataIC50:  35nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6921(2,5-dichloro-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-...)
Affinity DataIC50:  36nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6938(N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]...)
Affinity DataIC50:  37nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6923(3,5-diamino-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-i...)
Affinity DataIC50:  39nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6933(3,5-dimethoxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H...)
Affinity DataIC50:  41nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6926(N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]...)
Affinity DataIC50:  53nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6938(N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]...)
Affinity DataIC50:  57nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Dupont Pharmaceuticals

LigandPNGBDBM6930(2-hydroxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-ind...)
Affinity DataIC50:  60nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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