Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50015434
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155982BDBM50155982(8-(Butyl-ethyl-amino)-4-(2-chloro-4-methoxy-phenyl...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155974BDBM50155974(8-(Butyl-ethyl-amino)-4-(2,4-dichloro-phenyl)-6-me...)
Affinity DataIC50: 0.490nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155964BDBM50155964(8-(Butyl-ethyl-amino)-4-(2-chloro-5-fluoro-4-metho...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155967BDBM50155967(4-(2-Bromo-4-isopropyl-phenyl)-8-(butyl-ethyl-amin...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 20977BDBM20977(CHEMBL186097 | 8-[butyl(ethyl)amino]-4-(2,6-dimeth...)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155979BDBM50155979(8-(Butyl-ethyl-amino)-4-(2-chloro-4-isopropyl-phen...)
Affinity DataIC50: 0.910nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 20973BDBM20973(CHEMBL189089 | 8-[butyl(ethyl)amino]-4-(4-methoxy-...)
Affinity DataIC50: 0.920nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155975BDBM50155975(3-Chloro-4-(8-dipropylamino-6-methyl-2-oxo-2,3-dih...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155973BDBM50155973(4-(2-Chloro-5-fluoro-4-methoxy-phenyl)-8-(ethyl-is...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155960BDBM50155960(3-Chloro-4-[8-(cyclobutylmethyl-propyl-amino)-6-me...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155959BDBM50155959(4-[8-(Butyl-ethyl-amino)-6-methyl-2-oxo-2,3-dihydr...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155965BDBM50155965(4-(2-Chloro-4-isopropyl-phenyl)-8-[(2-methoxy-ethy...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155977BDBM50155977(4-[8-(Butyl-ethyl-amino)-6-methyl-2-oxo-2,3-dihydr...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155966BDBM50155966(4-(2-Bromo-4-isopropyl-phenyl)-8-(ethyl-furan-2-yl...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155961BDBM50155961(8-(Butyl-ethyl-amino)-4-(6-methoxy-2-methyl-pyridi...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155981BDBM50155981(4-(2-Bromo-phenyl)-8-(butyl-ethyl-amino)-6-methyl-...)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155969BDBM50155969(2-[8-(Butyl-ethyl-amino)-6-methyl-2-oxo-2,3-dihydr...)
Affinity DataIC50: 10nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50074364BDBM50074364(N*2*-(2-Bromo-4-isopropyl-phenyl)-N*4*-butyl-N*2*,...)
Affinity DataKi:  18nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155963BDBM50155963(8-[Bis-(2-methoxy-ethyl)-amino]-4-(2-chloro-4-isop...)
Affinity DataIC50: 18nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155972BDBM50155972(8-(Butyl-ethyl-amino)-4-(4-isopropyl-phenyl)-6-met...)
Affinity DataIC50: 49nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155970BDBM50155970(4-(2,4-Dichloro-phenyl)-8-(2-methoxy-butylamino)-6...)
Affinity DataIC50: 68nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155962BDBM50155962(4-{Ethyl-[4-(4-methoxy-2-methyl-phenyl)-6-methyl-2...)
Affinity DataIC50: 92nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155968BDBM50155968(4-(2-Bromo-4-isopropyl-phenyl)-6-methyl-8-morpholi...)
Affinity DataIC50: 126nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155971BDBM50155971(4-(2,4-Dichloro-phenyl)-8-(1-ethyl-propylamino)-6-...)
Affinity DataIC50: 198nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155976BDBM50155976(4-(2-Bromo-4-isopropyl-phenyl)-8-[ethyl-(3-methane...)
Affinity DataIC50: 305nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155978BDBM50155978(4-(2-Chloro-4-methoxy-phenyl)-8-ethylamino-6-methy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155980BDBM50155980(8-Butylamino-4-(2-chloro-4-methoxy-phenyl)-6-methy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed