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Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50015449
TargetGlutathione reductase(Plasmodium falciparum (isolate 3D7))
Université

Curated by ChEMBL
LigandPNGBDBM50096018(6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)H...)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibitory concentration against Plasmodium falciparum glutathione reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutathione reductase, mitochondrial(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50096018(6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)H...)
Affinity DataKi:  3.70E+3nMAssay Description:Inhibitory concentration against human glutathione reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutathione reductase, mitochondrial(Human)
Université

Curated by ChEMBL
LigandPNGBDBM24778(2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-meth...)
Affinity DataKi:  1.21E+4nMAssay Description:Inhibitory concentration against human glutathione reductase (In presence of glutathione disulfide)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutathione reductase, mitochondrial(Human)
Université

Curated by ChEMBL
LigandPNGBDBM24778(2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-meth...)
Affinity DataKi:  1.61E+4nMAssay Description:Inhibitory concentration against human glutathione reductase (In presence of NADPH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutathione reductase, mitochondrial(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50096018(6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)H...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibitory concentration against human glutathione reductase in the absence of glucose-6-phosphate dehydrogenase (G6PDH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutathione reductase, mitochondrial(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50096018(6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)H...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibitory concentration against human glutathione reductase in the the presence of 200 uM exogenous NADPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutathione reductase, mitochondrial(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50096018(6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)H...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibitory concentration against human glutathione reductase in the the presence of 200 uM exogenous NADPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutathione reductase, mitochondrial(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50096018(6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)H...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibitory concentration against human glutathione reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutathione reductase(Plasmodium falciparum (isolate 3D7))
Université

Curated by ChEMBL
LigandPNGBDBM50096018(6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)H...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibitory concentration against Plasmodium falciparum glutathione reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutathione reductase(Plasmodium falciparum (isolate 3D7))
Université

Curated by ChEMBL
LigandPNGBDBM50241461(3,7-bis(dimethylamino)phenothiazin-5-ium chloride ...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibitory concentration against Plasmodium falciparum glutathione reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutathione reductase(Plasmodium falciparum (isolate 3D7))
Université

Curated by ChEMBL
LigandPNGBDBM50156159(3-{5-[4-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen...)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibitory concentration against Plasmodium falciparum glutathione reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutathione reductase, mitochondrial(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50241461(3,7-bis(dimethylamino)phenothiazin-5-ium chloride ...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory concentration against human glutathione reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutathione reductase, mitochondrial(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50156161(5-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)
Affinity DataIC50:  2.27E+4nMAssay Description:Inhibitory concentration against human glutathione reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutathione reductase, mitochondrial(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50156159(3-{5-[4-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibitory concentration against human glutathione reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutathione reductase(Plasmodium falciparum (isolate 3D7))
Université

Curated by ChEMBL
LigandPNGBDBM50156161(5-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibitory concentration against Plasmodium falciparum glutathione reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed