Compile Data Set for Download or QSAR
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Found 17 Enz. Inhib. hit(s) with all data for entry = 50015505
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50156760((E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N...)
Affinity DataIC50:  4.51E+4nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50156763(1,4-bis(4-hydroxyphenethylamino)anthracene-9,10-di...)
Affinity DataIC50:  5.67E+4nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50156759(5-((2-(3,5-dichloro-2-hydroxybenzylideneamino)phen...)
Affinity DataIC50:  7.43E+4nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM27507(3-Pyridinecarboxamide | CHEMBL1140 | NAM | niacina...)
Affinity DataIC50:  1.01E+5nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50156771(4-(2-(4-(4-chlorophenyl)-5-mercapto-4H-1,2,4-triaz...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50156769(4-((4-(2,3-dihydro-1H-inden-2-yl)-5-hydroxy-4H-1,2...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50156767(3-(3-(4-(phenoxymethyl)phenyl)ureido)benzoic acid ...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50156768(2-((4-(4-(4-(2-hydroxybenzylideneamino)phenoxy)but...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50156773(2-(2-oxo-2-(4-(2-(trifluoromethyl)quinolin-4-yl)pi...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50156770(4-(3-(2-hydroxybenzamido)phenylamino)-4-oxobut-2-e...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50156772(5-(4-benzamido-2-methoxy-5-methylphenylamino)-5-ox...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50156765(2-((4-(3-(4-(2-hydroxybenzylideneamino)phenoxy)pro...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50156764(5-(9-oxo-9H-xanthen-2-yloxy)pentanoic acid | CHEMB...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50156762(2-(4-((2-(tert-butoxycarbonyl)-3-phenylpropanoylox...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50156761(6-(2-hydroxy-ethylsulfanyl)-2-(2-pyridin-2-yl-ethy...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50156758(CHEMBL225118 | bis(4-((2-hydroxyethyl)(methyl)amin...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50156766(4-((4-(4-(3,4-dihydroxybenzylideneamino)benzyl)phe...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed