Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50042232
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157445BDBM50157445(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157461BDBM50157461(3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-ph...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157458BDBM50157458(3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-ph...)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157446BDBM50157446(3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-ph...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157464BDBM50157464(3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-ph...)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157470BDBM50157470(3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-ph...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157475BDBM50157475(3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-ph...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157447BDBM50157447(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157459BDBM50157459(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157469BDBM50157469(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157466BDBM50157466(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157463BDBM50157463(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157465BDBM50157465(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50: 11nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157443BDBM50157443(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50: 16nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50117056BDBM50117056((S)-2-(2-Bromo-6-methyl-benzoylamino)-3-[4-(2,6-di...)
Affinity DataIC50: 17nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157474BDBM50157474(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50: 23nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157467BDBM50157467(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2-...)
Affinity DataIC50: 48nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157455BDBM50157455(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-[3-(iso...)
Affinity DataIC50: 54nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16801BDBM16801(CHEMBL91485 | N-Acyl-4-arylphenylalanine analogue....)
Affinity DataIC50: 61nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157444BDBM50157444(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50: 85nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157450BDBM50157450(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-[3-(iso...)
Affinity DataIC50: 620nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157448BDBM50157448(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(3,...)
Affinity DataIC50: 650nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157456BDBM50157456(2-{3-[(Cyclohex-3-enecarbonyl)-isobutyl-amino]-phe...)
Affinity DataIC50: 930nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157471BDBM50157471(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-[3-(iso...)
Affinity DataIC50: 940nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157468BDBM50157468(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[iso...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157457BDBM50157457(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[iso...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157476BDBM50157476(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157449BDBM50157449(2-[3-(Benzoyl-isobutyl-amino)-phenyl]-3-[4-(2,6-di...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157462BDBM50157462(2-[3-(Acetyl-isobutyl-amino)-phenyl]-3-[4-(2,6-dic...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157473BDBM50157473(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-[3-(met...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157452BDBM50157452(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-(3-{iso...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157453BDBM50157453(2-{3-[Benzyl-(2,2-dimethyl-propionyl)-amino]-pheny...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157454BDBM50157454(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(fu...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157460BDBM50157460(2-[3-(tert-Butoxycarbonyl-isobutyl-amino)-phenyl]-...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157451BDBM50157451(2-{3-[(Cyclohex-3-enecarbonyl)-amino]-phenyl}-3-[4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157472BDBM50157472(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-(3-phen...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed