Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50042010
LigandChemical structure of BindingDB Monomer ID 50391000BDBM50391000(CB-01-11 | RIFAMYCIN)
Affinity DataIC50: 230nMAssay Description:TP_TRANSPORTER: inhibition of estradiol-17beta-glucuronide uptake(estradiol-17beta-glucuronide:0.02uM) in OATP1B1-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 22164BDBM22164(CI 981 | CHEMBL1487 | (3R,5R)-7-[2-(4-fluorophenyl...)
Affinity DataIC50: 870nMAssay Description:TP_TRANSPORTER: inhibition of estradiol-17beta-glucuronide uptake(estradiol-17beta-glucuronide:0.02uM) in OATP1B1-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50011032BDBM50011032(CHEMBL333687 | Atorvastatin lactone | 5-(4-Fluoro-...)
Affinity DataIC50: 2.60E+3nMAssay Description:TP_TRANSPORTER: inhibition of estradiol-17beta-glucuronide uptake(estradiol-17beta-glucuronide:0.02uM) in OATP1B1-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 18375BDBM18375(Simvastatin acid | (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-...)
Affinity DataIC50: 3.60E+3nMAssay Description:TP_TRANSPORTER: inhibition of estradiol-17beta-glucuronide uptake(estradiol-17beta-glucuronide:0.02uM) in OATP1B1-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50406681BDBM50406681(MEVINOLINIC ACID)
Affinity DataIC50: 4.00E+3nMAssay Description:TP_TRANSPORTER: inhibition of estradiol-17beta-glucuronide uptake(estradiol-17beta-glucuronide:0.02uM) in OATP1B1-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50139181BDBM50139181(2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(...)
Affinity DataIC50: 9.70E+3nMAssay Description:TP_TRANSPORTER: inhibition of estradiol-17beta-glucuronide uptake(estradiol-17beta-glucuronide:0.02uM) in OATP1B1-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 34168BDBM34168(cid_53232 | SMR000058779 | MLS000069585 | LOVASTAT...)
Affinity DataIC50: 1.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of calcein-AM efflux in MDR1-expressing MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139181BDBM50139181(2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of calcein-AM efflux in MDR1-expressing MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011032BDBM50011032(CHEMBL333687 | Atorvastatin lactone | 5-(4-Fluoro-...)
Affinity DataIC50: 1.40E+4nMAssay Description:TP_TRANSPORTER: inhibition of calcein-AM efflux in MDR1-expressing MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50011032BDBM50011032(CHEMBL333687 | Atorvastatin lactone | 5-(4-Fluoro-...)
Affinity DataIC50: 1.50E+4nMAssay Description:TP_TRANSPORTER: inhibition of calcein-AM efflux in MRP2-expressing MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50012278BDBM50012278(VINBLASTINE SULFATE | (2ALPHA,2''BETA,3BETA,4ALPHA...)
Affinity DataIC50: 2.10E+4nMAssay Description:TP_TRANSPORTER: inhibition of calcein-AM efflux in MRP2-expressing MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50139181BDBM50139181(2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(...)
Affinity DataIC50: 2.50E+4nMAssay Description:TP_TRANSPORTER: inhibition of calcein-AM efflux in MRP2-expressing MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 34168BDBM34168(cid_53232 | SMR000058779 | MLS000069585 | LOVASTAT...)
Affinity DataIC50: 2.80E+4nMAssay Description:TP_TRANSPORTER: inhibition of estradiol-17beta-glucuronide uptake(estradiol-17beta-glucuronide:0.02uM) in OATP1B1-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012278BDBM50012278(VINBLASTINE SULFATE | (2ALPHA,2''BETA,3BETA,4ALPHA...)
Affinity DataIC50: 2.90E+4nMAssay Description:TP_TRANSPORTER: inhibition of calcein-AM efflux in MDR1-expressing MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed